Basic information Reaction Safety Supplier Related

(+)-1,2-BIS[(2S,5S)-2,5-DIMETHYLPHOSPHOLANO]BENZENE

Basic information Reaction Safety Supplier Related

(+)-1,2-BIS[(2S,5S)-2,5-DIMETHYLPHOSPHOLANO]BENZENE Basic information

Product Name:
(+)-1,2-BIS[(2S,5S)-2,5-DIMETHYLPHOSPHOLANO]BENZENE
Synonyms:
  • (+)-1,2-Bis((2S,5S)-2,5-diMethylphospholano)benzene (S,S)-Me-DUPHOS
  • (+)-1,2-Bis[(2S,5S)-2,5-diMethylphospholano]benzene kanata purity
  • (S,S)-ME-DUPHOS
  • (S,S)-METHYL-DUPHOS
  • (+)-1,2-Bis((2S,5S)-2,5-dimethylphospholano)benzene,98+%(S,S)-Me-DUPHOS
  • (+)-1,2-BIS[(2S,5S)-2,5-DIMETHYLPHOSPHOLANO]BENZENE
  • (2S,2'S,5S,5'S)-2,2',5,5'-TETRAMETHYL-1,1'-(1,2-PHENYLENE)DIPHOSPHOLANE
  • (2S,2'S,5S,5'S)-2,2',5,5'-TETRAMETHYL-1,1'-(O-PHENYLENE)DIPHOSPHOLANE
CAS:
136735-95-0
MF:
C18H28P2
MW:
306.36
Product Categories:
  • organophosphine ligand
Mol File:
136735-95-0.mol
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(+)-1,2-BIS[(2S,5S)-2,5-DIMETHYLPHOSPHOLANO]BENZENE Chemical Properties

Melting point:
67-76 °C
alpha 
D25 +476± 5° (c = 1 in hexane)
Boiling point:
415.0±15.0 °C(Predicted)
storage temp. 
under inert gas (nitrogen or Argon) at 2-8°C
form 
crystal
color 
white
Water Solubility 
Insoluble in water.
Sensitive 
Air Sensitive
BRN 
4810602
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Safety Information

Hazard Codes 
Xi
Risk Statements 
36/37/38
Safety Statements 
26-36
WGK Germany 
3
1-10

MSDS

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(+)-1,2-BIS[(2S,5S)-2,5-DIMETHYLPHOSPHOLANO]BENZENE Usage And Synthesis

Reaction

  1. The DUPHOS family of catalysts is highly efficient for the asymmetric hydrogenation of various substituted acetamidoacrylates and enol acetates yielding products of high enantiomeric excesses. Efficient ligand for the asymmetric hydrogenation of imines, enamines, and enamides.
  2. Asymmetric hydrogenation of vinyl alcohols.
  3. Catalyst used for the asymmetric hydrogenation of enol phosphonates.
  4. Asymmetric hydrogenation of allylic alcohols.
  5. Ligand for the catalytic asymmetric [4+1] cycloaddition of vinylallenes with CO.
  6. Ligand for the Rh-catalyzed asymmetric enyne cycloisomerization.
  7. Catalytic enantioselective addition of dialkylzinc to N-Diphenylphosphinoylimines.
  8. Palladium-catalyzed asymmetric phosphination.
  9. Palladium-catalyzed asymmetric hydrogenation of carbonyls.
  10. Palladium-catalyzed 1,4 arylation of α, β-unsaturated ketones.
  11. Asymmetric, Ir-catalyzed, [2+2+2] cycloaddition.
  12. Asymmertric palladium-catalyzed synthesis of 2-methyl-indolines via C–H activation.
  13. Copper-catalyzed monoborylation of 1,3-Dienes.
  14. Rhodium-catalyzed enantioselective transmetalation.
  15. CuH-catalyzed hydroamination of styrenes.



Uses

It is a DuPhos and BPE ligands which are highly efficient privileged ligands.

(+)-1,2-BIS[(2S,5S)-2,5-DIMETHYLPHOSPHOLANO]BENZENESupplier

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