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N-BOC-cis-4-fluoro-L-proline

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N-BOC-cis-4-fluoro-L-proline Basic information

Product Name:
N-BOC-cis-4-fluoro-L-proline
Synonyms:
  • (2S,4S)-N-Boc-4-fluoropyrrolidine-2-carboxy lic acid
  • Boc-cis-L-4-Fluoroproline
  • 4S)-1-(tert-Butoxycarbonyl)-4-fluoro-2-pyrrolidinecarboxylic Acid
  • (2S,4S)-N-Boc-cis-4-Fluoro-L-proline
  • (2S,4S)-4-Fluoropyrrolidine-2-carboxylic acid, N-BOC protected
  • cis-4-Fluoro-L-proline, N-BOC protected
  • (2S,4S)-1-Boc-4-fluoro-2-pyrrolidinecarboxylic Acid N-(tert-Butoxycarbonyl)-cis-4-fluoro-L-proline N-Boc-cis-4-fluoro-L-proline
  • Boc-(2S,4S)-4-fluoro-pyrrolidine-2-carboxylic acid, Boc-flp-OH
CAS:
203866-13-1
MF:
C10H16FNO4
MW:
233.24
Product Categories:
  • Carboxylic Acids (Chiral)
  • Chiral Building Blocks
  • Synthetic Organic Chemistry
  • Chiral Building Blocks
  • Heterocyclic Building Blocks
  • Pyrrolidines
  • Nitrogen cyclic compounds
  • 11
Mol File:
203866-13-1.mol
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N-BOC-cis-4-fluoro-L-proline Chemical Properties

Melting point:
157-161.°C
Boiling point:
346.0±42.0 °C(Predicted)
Density 
1.24±0.1 g/cm3(Predicted)
refractive index 
-57 ° (C=1, MeOH)
storage temp. 
Keep in dark place,Sealed in dry,Room Temperature
form 
powder to crystal
pka
3.53±0.40(Predicted)
color 
White to Almost white
optical activity
[α]22/D 71.0±5°, c = 1 in chloroform
InChIKey
YGWZXQOYEBWUTH-BQBZGAKWSA-N
CAS DataBase Reference
203866-13-1(CAS DataBase Reference)
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Safety Information

Hazard Codes 
Xi
Risk Statements 
36/37/38
Safety Statements 
26
WGK Germany 
3
HazardClass 
IRRITANT
HS Code 
29339900
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N-BOC-cis-4-fluoro-L-proline Usage And Synthesis

Chemical Properties

White powder

Uses

N-Boc-cis-4-fluoro-L-proline can be used as a substrate in the preparation of:

  • α4β2 Receptor ligands bearing pyrrolidine nucleus.
  • β-Amino pyrrolidine-2-carbonitrile derivatives as possible dipeptidyl peptidase IV (DPP4) inhibitors.

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