3BETA-HYDROXY-5-CHOLESTENE 3-HEMISUCCINATE TRIS SALT Chemical Properties

storage temp. 

-20°C

form 

powder

color 

White to off-white

biological source

synthetic (organic)

InChIKey

SLDYONDUXRBLLR-XTCKSVDZSA-N

SMILES

NC(CO)(CO)CO.CC(C)CCC[C@@H](C)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@H](CC[C@]4(C)[C@H]3CC[C@]12C)OC(=O)CCC(O)=O

Safety Information

WGK Germany 

3

Storage Class

11 - Combustible Solids

MSDS

• Language:English Provider:SigmaAldrich

3BETA-HYDROXY-5-CHOLESTENE 3-HEMISUCCINATE TRIS SALT Usage And Synthesis

Uses

Cholesteryl hemisuccinate tris salt has been used:

• to prepare solubilization buffer for glucan synthase assay
• to prepare immunoprecipitation buffer for immobilization of opioid receptors on paramagnetic beads.
• as a membrane stabilizer for liposomes and protein synaptogyrin-1
• as a component of a folate-modified self-microemulsifying drug delivery system.
• with N-dodecyl β-D-maltoside (DDM) to solubilize erythrocyte ghosts and chemokine receptor CCR1
• for protein solubilization

Biochem/physiol Actions

Cholesteryl hemisuccinate is an ionizable anionic detergent that stabilizes large unilamellar vesicles. These liposome vesicles act as delivery agents for anticancer drugs, oligonucleotides and antibiotics. Cholesteryl succinate also reportedly exhibits antiproliferative activity and may be clinically useful as antitumor agent.

3BETA-HYDROXY-5-CHOLESTENE 3-HEMISUCCINATE TRIS SALT(102601-49-0)Related Product Information

• Tris(hydroxymethyl)aminomethane
• 5-CHOLESTENE
• Hydrogen
• Cholesteryl hemisuccinate
• 3BETA-HYDROXY-5-CHOLESTENE 3-HEMISUCCINATE TRIS SALT
• Tris(hydroxymethyl)aminomethane acetate salt
• Cholesteryl acetate