Rebaudioside A Chemical Properties

Melting point:

235°C(lit.)

Boiling point:

1102.8±65.0 °C(Predicted)

Density 

1.59±0.1 g/cm3(Predicted)

vapor pressure 

0-1198Pa at 20-50℃

FEMA 

4601 | REBAUDIOSIDE A

storage temp. 

Inert atmosphere,2-8°C

solubility 

DMSO (Slightly), Methanol (Slightly), Water (Sparingly)

pka

12.51±0.70(Predicted)

color 

White to Off-White

optical activity

[α]/D -33.0±3.0°, c = 1% in H2O

BRN 

6470556

Stability:

Hygroscopic

LogP

-1-2.61 at 20-25℃ and pH7

Safety Information

Safety Statements 

24/25

WGK Germany 

3

RTECS 

NZ8174800

HS Code 

29389090

Rebaudioside A Usage And Synthesis

Description

Rebaudioside A is a natural non-caloric sweetener. It is one of the predominant steviol glycosides isolated from S. rebaudiana leaves. It increases glucagon-like peptide 1 (GLP-1) secretion in a 2-dimensional mouse intestine model. In a two bottle preference test, mice drink more water containing rebaudioside A than unsweetened water, though saccharin-sweetened water is still preferred. Rebaudioside A is metabolized by gut microbiota to steviol , a compound whose safety is widely studied. Consumption of rebaudioside A formulations by pre-diabetic patients did not increase fasting or 2 hour plasma glucose levels or insulin levels.

Chemical Properties

White powder

Uses

Rebaudioside A is a glycoside from the stevia plant. Rebaudioside A is used as a sweetener with sweetness about 300 times that of sugar with negligible effect on blood glucose. As a result, Rebaudiosi de A is known for its application in treatment of many diseases like diabetes, high blood pressure and weight loss in some places. It is used as a food additive and in dietary supplements.

Uses

natural sweetener to diabetics and others on carbohydrate-controlled diets

Uses

Rebaudioside A is a natural, highly processed calorie free sweetener obtained from the leaves of the plant stevia rebaudiana bertoni. it is a steviol glycoside in which the steviol’s carboxyl and hydroxyl hydrogen atom is replaced with glucose, it has three linked glucose molecules at the hydroxyl site. rebaudiana (reb a) is 300–400 times sweeter than sugar and the least bitter of the glycosides. it is ph and heat stable with good solubility in water. uses include beverages, table top sweetener, general foods. it is also termed reb a, stevia extract, stevia.

Definition

Rebaudioside A is a rebaudioside that is rubusoside in which the hydroxy groups at positions 3 and 4 of the beta-D-glucopyranosyloxy group at the 13alpha position have both been converted to the corresponding beta-D-glucopyranoside. It has a role as a sweetening agent. It is a beta-D-glucoside, a tetracyclic diterpenoid and a rebaudioside. It derives from a rubusoside and a beta-D-Glcp-(1->2)-[beta-D-Glcp-(1->3)]-beta-D-Glcp.

benefits

Zero calories
No carbohydrate
Does not raise blood glucose or insulin levels (Zero Index Glycemic), safe for people with diabetes
Keto, Vegan, and Gluten-Free

Biological Activity

Rebaudioside A is a natural non-caloric sweetener. It is one of the predominant steviol glycosides isolated from S. rebaudiana leaves. It increases glucagon-like peptide 1 (GLP-1) secretion in a 2-dimensional mouse intestine model. In a two bottle preference test, mice drink more water containing rebaudioside A than unsweetened water, though saccharin-sweetened water is still preferred. Rebaudioside A is metabolized by gut microbiota to steviol, a compound whose safety is widely studied. Consumption of rebaudioside A formulations by pre-diabetic patients did not increase fasting or 2 hour plasma glucose levels or insulin levels.

Safety

High-purity (95% minimum) of individual or combined steviol glycosides can be considered as GRAS (Generally Recognized as Safe) by the FDA. For example, FDA had no questions regarding Guilin Layn's conclusion that its reb A (≥97% by weight (w/w)) is GRAS as a table top sweetener and as a general purpose sweetener in foods, excluding meat and poultry products and infant formulas.
Its safety has also been approved by the EFSA, JECFA, FSANZ and other authorities.

Rebaudioside A(58543-16-1)Related Product Information

• CYCLOPENTADECANE
• METHYL CYCLOHEXANEACETATE
• ETHYL CYCLOHEXYLACETATE
• D-(-)-GULOSE
• Steviol
• Rebaudioside A
• Isophytol
• DELTA 12 CIS TRIDECENOIC ACID METHYL ESTER
• 4-tert-Butylcyclohexanol
• 1-VINYLCYCLOHEXANOL 97
• CIS-4-TERT-BUTYLCYCLOHEXANOL
• CYCLOPENTADECANOL
• BUTYL UNDECYLENATE
• REBAUDIOSIDE A(P),REBAUDIOSIDE A(RG)
• REBAUDIOSIDE B(P)
• Stevioside
• propyl cyclohexaneacetate
• hexyl pivalate