6-Nitrophthalide Chemical Properties

Melting point:

140-145 °C(lit.)

Boiling point:

311.63°C (rough estimate)

Density 

1.4908 (rough estimate)

refractive index 

1.5160 (estimate)

storage temp. 

Sealed in dry,Room Temperature

form 

Crystalline Powder

color 

Pale yellow

Water Solubility 

0.4g/L(25 ºC)

CAS DataBase Reference

610-93-5(CAS DataBase Reference)

Safety Information

Hazard Codes 

Xi

Risk Statements 

20/21/22-36/37/38

Safety Statements 

24/25-37-26

WGK Germany 

3

HazardClass 

IRRITANT

HS Code 

29322090

MSDS

• Language:English Provider:SigmaAldrich
• Language:English Provider:ACROS
• Language:English Provider:ALFA

6-Nitrophthalide Usage And Synthesis

Chemical Properties

pale yellow crystalline powder

Uses

6-Nitrophthalide is a fluorescent heterocycle that can be used as a probe for specific inhibition. It is homologous to other fluorescent probes such as fluorescein, nitrobenzene, and nitrophenol. It has been shown to have inhibitory properties against triazole and dipole, which are catalytic asymmetric. 6-Nitrophthalide has also been shown to have the ability to inhibit the oxidation of aldehydes.

Preparation

6-Nitrophthalide is synthesized from 2-nitrobenzaldehyde via a two-step process, and then reacted with methyl iodide.

Application

6-Nitrophthalide has been used in the preparation of 3-bromo-6-nitrophthalide. It undergoes reductive methylation to form 6-dimethylaminophthalide.

6-Nitrophthalide(610-93-5)Related Product Information

• 1,2,4,5-Tetrachlorobenzene
• 3-Nitrobenzaldehyde
• 4-(4-NITROPHENYL)MORPHOLINE
• Phthalide
• FTHALIDE
• 4-Nitrophthalide
• 5 NITROPHTHALIDE
• 4,5,6-triethoxy-7-nitrophthalide
• 6-NITRO-3-PHENYL-3H-ISOBENZOFURAN-1-ONE
• 6-Nitrophthalide
• 5-CHLORO-3-HYDROXY-6-NITRO-3H-ISOBENZOFURAN-1-ONE
• NITROFLUORESCEIN, ISOMER 1
• 4-Nitrophthalic anhydride