Disodium 7,7'-(carbonyldiimino)bis(4-hydroxynaphthalene-2-sulphonate) CAS#: 20324-87-2

Disodium 7,7'-(carbonyldiimino)bis(4-hydroxynaphthalene-2-sulphonate) Basic information

Product Name:

Disodium 7,7'-(carbonyldiimino)bis(4-hydroxynaphthalene-2-sulphonate)

Synonyms:

4-hydroxy-7-[(5-hydroxy-7-sulfonatonaphthalen-2-yl)carbamoylamino]naphthalene-2-sulfonate
AMI-1 - AMI-1 sodium salt
AMI-1;AMI 1;AMI1
disodium 4-hydroxy-7-[(5-hydroxy-7-sulfonato-2-naphthyl)carbamoylamino]naphthalene-2-sulfonate
disodium 4-hydroxy-7-[(5-hydroxy-7-sulfonato-naphthalen-2-yl)carbamoylamino]naphthalene-2-sulfonate
disodium 4-hydroxy-7-[(5-hydroxy-7-sulfonatonaphthalen-2-yl)carbamoylamino]naphthalene-2-sulfonate
J acid urea,disodiuM salt 70%
7,7'-(carbonyldiimino)bis(4-hydroxy-2-naphthalenesulfonic acid) disodium salt

CAS:

20324-87-2

MF:

C21H17N2NaO9S2

MW:

528.48

EINECS:

243-735-4

Product Categories:

Inhibitors

Mol File:

20324-87-2.mol

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Disodium 7,7'-(carbonyldiimino)bis(4-hydroxynaphthalene-2-sulphonate) Chemical Properties

storage temp.: under inert gas (nitrogen or Argon) at 2-8°C
solubility: insoluble in EtOH; insoluble in DMSO; ≥19.1 mg/mL in H2O
form: Brown solid.
color: Light brown to brown
EPA Substance Registry System: 2-Naphthalenesulfonic acid, 7,7'-(carbonyldiimino)bis[4-hydroxy-, disodium salt (20324-87-2)

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Disodium 7,7'-(carbonyldiimino)bis(4-hydroxynaphthalene-2-sulphonate) Usage And Synthesis

Uses

AMI-1 is a Histone Methyltransferase (HMT) inhibitor.

Biological Activity

potent, cell permeable and specific protein arginine n-methyltransferase 1 (prmt1) inhibitor (ic50 = 8, 8 μm), does not compete for the adomet (s-adenosyl-l-methionine, sam) binding site, blocks peptide substrate binding, hiv-1 rt polymerase inhibitor (ic50 = 5, 0 μm).

Disodium 7,7'-(carbonyldiimino)bis(4-hydroxynaphthalene-2-sulphonate)Supplier

Shanghai Boyle Chemical Co., Ltd.

Tel
Email: sales@boylechem.com

Spectrum Chemical Manufacturing Corp.

Tel: 021-021-021-67601398-809-809-809 15221380277
Email: marketing_china@spectrumchemical.com

Dalian Meilun Biotech Co., Ltd.

Tel: 0411-62910999 13889544652
Email: meilunui@163.com

Jiangsu Aikon Biopharmaceutical R&D co.,Ltd.

Tel: 025-66099280 17798518460
Email: cfzhang@aikonchem.com

Haoyuan Chemexpress Co., Ltd.

Tel: 021-58950125
Email: info@chemexpress.com

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