Pikamilone
Pikamilone Basic information
- Product Name:
- Pikamilone
- Synonyms:
-
- 4-((Pyridine-3-carbonyl)-amino)-butyric acid
- Pikamiline
- PikamiloneHCl
- 3-[(3-Carboxypropyl)carbamoyl]pyridine
- PIKAMILON
- 4-Nicotinoylamino-butylric acid
- PIKAMILONE HYDROCHLORIDE
- NICOTINOYL-GABA
- CAS:
- 34562-97-5
- MF:
- C10H12N2O3
- MW:
- 208.21
- EINECS:
- 1308068-626-2
- Product Categories:
-
- Other APIs
- API
- Heterocycles
- Chemistry
- 34562-97-5
- Mol File:
- 34562-97-5.mol
Pikamilone Chemical Properties
- Melting point:
- 211.0 to 215.0 °C
- Boiling point:
- 522.4±30.0 °C(Predicted)
- Density
- 1.245
- storage temp.
- Inert atmosphere,Room Temperature
- solubility
- DMSO (Slightly, Heated), Methanol (Slightly)
- form
- Solid
- pka
- 4.60±0.10(Predicted)
- color
- White to Off-White
- CAS DataBase Reference
- 34562-97-5(CAS DataBase Reference)
Safety Information
- Hazard Codes
- Xi
- HazardClass
- IRRITANT
- HS Code
- 2933599590
Pikamilone Usage And Synthesis
Description
Pikamilone is a drug having a central (vegetotropic and vascular) and peripheral (vasodilating) mechanisms of action.
Clinical Use
Pikamilone treatment of benign prostatic hyperplasia
Pikamilone is an original drug of Russian produce having a central (vegetotropic and vascular) and peripheral (vasodilating) mechanisms of action. The drug was tried as monotherapy in elderly patients with benign prostatic hyperplasia who had symptoms of the lower urinary tracts to estimate its effect on local and general mechanisms of nervous and vascular regulation of detruzor function in infravesical obstruction.
https://pubmed.ncbi.nlm.nih.gov/11150159/
Uses
anti-cancer agent
Uses
Nicotinoyl-γ-aminobutyric Acid is a pro-drug of γ-Aminobutyric Acid (A602920). Studies show that Nicotinoyl-γ-aminobutyric Acid is involved in the regulation of the processes in the brain of streptozotocin-induced diabetic rats.
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Pikamilone(34562-97-5)Related Product Information
- Pyridine
- Glycine
- CARBONYL SULFIDE
- PYRAZOPHOS
- L(+)-2-Aminobutyric acid
- 3-Aminopyridine
- 4-Aminobutyric acid
- DL-3-Aminobutyric acid
- 6-Aminocaproic acid
- DL-2-Aminobutyric acid
- D-2-Aminobutyric acid
- r-Amino Butryric Acid
- Pikamilone sodium
- N-(5-hydroxynicotinoyl)-L-glutamic acid
- Glutamic acid, N-(2-chloronicotinoyl)-
- Pikamilone
- DL-2,4-Diaminobutanoic acid
- 1-[(2-hydroxypyridin-3-yl)carbonyl]piperidine-4-carboxylic acid