L(+)-2-Aminobutyric acid
L(+)-2-Aminobutyric acid Basic information
- Product Name:
- L(+)-2-Aminobutyric acid
- Synonyms:
-
- L-2-AMINO-N-BUTYRIC ACID
- L-2-AMINOBUTANOIC ACID
- L-(+)-2-AMINOBUTYRIC ACID
- L-2-AMINOBUTYRIC ACID
- L-ABU
- L-ALPHA-AMINO-N-BUTYRIC ACID
- L-ALPHA-AMINOBUTYRIC ACID
- H-ABU-OH
- CAS:
- 1492-24-6
- MF:
- C4H9NO2
- MW:
- 103.12
- EINECS:
- 216-083-3
- Product Categories:
-
- Amino Acids 13C, 2H, 15N
- Amino Acids & Derivatives
- Unusual Amino Acids
- Chiral Reagents
- amino acid
- Odevixibat
- bc0001
- Mol File:
- 1492-24-6.mol
L(+)-2-Aminobutyric acid Chemical Properties
- Melting point:
- 300 °C
- alpha
- 21.6 º (c=2, 5N HCl)
- Boiling point:
- 215.2±23.0 °C(Predicted)
- Density
- 1.2300 (estimate)
- refractive index
- 1.4650 (estimate)
- storage temp.
- room temp
- solubility
- 22.7 g/100 mL (22°C)
- pka
- 2.29(at 25℃)
- form
- Crystalline Powder
- color
- White to beige
- Water Solubility
- 22.7 g/100 mL (22 ºC)
- Merck
- 14,428
- BRN
- 1720935
- InChIKey
- QWCKQJZIFLGMSD-VKHMYHEASA-N
- CAS DataBase Reference
- 1492-24-6(CAS DataBase Reference)
- NIST Chemistry Reference
- (l)-2-Aminobutanoic acid(1492-24-6)
- EPA Substance Registry System
- Butanoic acid, 2-amino-, (2S)- (1492-24-6)
MSDS
- Language:English Provider:L-2-Aminobutanoic acid
- Language:English Provider:ACROS
- Language:English Provider:SigmaAldrich
- Language:English Provider:ALFA
L(+)-2-Aminobutyric acid Usage And Synthesis
Chemical Properties
White Crystalline Solid
Uses
aminobutyric acid is an amino acid with water-binding properties and possible anti-inflammatory capacities.
Uses
L-(+)-2-Aminobutyric acid is used in the biosynthesis of nonribosomal peptides. It acts as a receptor antagonist. It is also used as a chiral reagent. Further, it is used in the determination of substrate of glutamyl cysteine acid synthase. In addition to this, it is also utilized as a drug intermediate.
Definition
ChEBI: An optically active form of alpha-aminobutyric acid having L-configuration.
Synthesis Reference(s)
Journal of the American Chemical Society, 68, p. 450, 1946 DOI: 10.1021/ja01207a032
General Description
L-2-Aminobutyric acid is synthesized from L-threonine and L-aspartic acid through a ?-transamination reaction. It is an L-alanine analogue with an ethyl side chain.
Biochem/physiol Actions
L-α-Aminobutyric acid (AABA) is an isomer of the non-natural amino acid aminobutyric acid with activity in the γ-glutamyl cycle that regulates glutathione biosynthesis. Recently AABA has been studied as a supplement to in vitro maturation medium (NCSU 23 medium) for culture of oozytes and embryos. This product has been qualified for use in cell culture. AABA is also used as a substitute amino acid for alanine in studies on peptide function.
Purification Methods
Crystallise butyrine from aqueous EtOH, and the melting point depends on heating rate but has m 303o in a sealed tube. [Greenstein & Winitz The Chemistry of the Amino Acids J. Wiley, Vol 3 p 2399 IR: 2401 1961, Beilstein 4 III 1294, 4 IV 2584.]
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