euscaphic acid Chemical Properties

Melting point:

262-264 °C(Solv: chloroform (67-66-3); methanol (67-56-1))

Boiling point:

602.7±55.0 °C(Predicted)

Density 

1.19±0.1 g/cm3(Predicted)

storage temp. 

-20°C Freezer

solubility 

Methanol (Slightly), Pyridine (Slightly)

form 

Solid

pka

4.47±0.70(Predicted)

color 

White to Off-White

euscaphic acid Usage And Synthesis

Uses

Euscaphic Acid is a hypoglycemic natural product from Folium Eriobotryae with anti-inflammatory properties. Euscaphic Acid also downregulates NF-κB activations and inhibits LPS-induced inflammatory responses.

Definition

ChEBI: Euscaphic acid is a pentacyclic triterpenoid that is urs-12-en-28-oic acid substituted by hydroxy groups at positions 2, 3 and 19 respectively (the 2alpha,3alpha-stereoisomer). It has been isolated from the leaves of Rosa laevigata. It has a role as a plant metabolite. It is a pentacyclic triterpenoid, a hydroxy monocarboxylic acid and a triol. It derives from a hydride of an ursane.

target

LDL | NO | PGE | TNF-α | NOS | COX | NF-kB | JNK | ERK | p38MAPK | Calcium Channel | Sodium Channel | ATPase | Potassium Channel | IkB | IKK

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