euscaphic acid Chemical Properties

Melting point:

262-264 °C(Solv: chloroform (67-66-3); methanol (67-56-1))

Boiling point:

602.7±55.0 °C(Predicted)

Density 

1.19±0.1 g/cm3(Predicted)

storage temp. 

-20°C Freezer

solubility 

Methanol (Slightly), Pyridine (Slightly)

form 

Solid

pka

4.47±0.70(Predicted)

color 

White to Off-White

InChIKey

OXVUXGFZHDKYLS-SPQMEPECSA-N

SMILES

C[C@H]1[C@](O)(C)[C@H]2[C@@](C(=O)O)(CC[C@]3([C@@]4(C)[C@@H]([C@@]5(C(CC4)C(C)(C)[C@H](O)[C@H](O)C5)C)CC=C32)C)CC1

euscaphic acid Usage And Synthesis

Chemical Properties

White crystalline powder, soluble in organic solvents such as methanol, ethanol, DMSO, etc., derived from the roots of golden cherry and the seeds of Fujian wild jasmine.

Uses

Euscaphic Acid is a hypoglycemic natural product from Folium Eriobotryae with anti-inflammatory properties. Euscaphic Acid also downregulates NF-κB activations and inhibits LPS-induced inflammatory responses.

Definition

ChEBI: Euscaphic acid is a pentacyclic triterpenoid that is urs-12-en-28-oic acid substituted by hydroxy groups at positions 2, 3 and 19 respectively (the 2alpha,3alpha-stereoisomer). It has been isolated from the leaves of Rosa laevigata. It has a role as a plant metabolite. It is a pentacyclic triterpenoid, a hydroxy monocarboxylic acid and a triol. It derives from a hydride of an ursane.

target

LDL | NO | PGE | TNF-α | NOS | COX | NF-kB | JNK | ERK | p38MAPK | Calcium Channel | Sodium Channel | ATPase | Potassium Channel | IkB | IKK

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