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5,7-dihydroxy-3-(3-hydroxy-4,5-dimethoxyphenyl)-6-methoxy-4-benzopyrone

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5,7-dihydroxy-3-(3-hydroxy-4,5-dimethoxyphenyl)-6-methoxy-4-benzopyrone Basic information

Product Name:
5,7-dihydroxy-3-(3-hydroxy-4,5-dimethoxyphenyl)-6-methoxy-4-benzopyrone
Synonyms:
  • 5,7-Dihydroxy-3-(3-hydroxy-4,5-dimethoxyphenyl)-6-methoxy-4H-1-benzopyran-4-one
  • 5,7-dihydroxy-3-(3-hydroxy-4,5-dimethoxyphenyl)-6-methoxy-4-benzopyrone
  • 5,7-dihydroxy-3-(3-hydroxy-4,5-dimethoxyphenyl)-6-methoxychromen-4-one
  • Rrigenin
  • 4H-1-Benzopyran-4-one, 5,7-dihydroxy-3-(3-hydroxy-4,5-dimethoxyphenyl)-6-methoxy-
  • 5,7-Dihydroxy-3-(3-hydroxy-4,5-dimethoxyphenyl)-6-methoxy-4H-chromen-4-one
  • inhibit,cancer,lung,transition,metastasis,Irigenin,Integrin,apoptosis,Epithelial-Mesenchymal,C-C,TRAIL,EDA,gastric,loop,carcinoma,Inhibitor
CAS:
548-76-5
MF:
C18H16O8
MW:
360.31
EINECS:
208-958-3
Mol File:
548-76-5.mol
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5,7-dihydroxy-3-(3-hydroxy-4,5-dimethoxyphenyl)-6-methoxy-4-benzopyrone Chemical Properties

Melting point:
189-192℃
Boiling point:
646.1±55.0 °C(Predicted)
Density 
1.461±0.06 g/cm3 (20 ºC 760 Torr)
storage temp. 
2-8°C
solubility 
Soluble in ethanol and methan
form 
powder
pka
6.36±0.20(Predicted)
color 
White
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5,7-dihydroxy-3-(3-hydroxy-4,5-dimethoxyphenyl)-6-methoxy-4-benzopyrone Usage And Synthesis

Uses

Irigenin is identified as an α-glucosidase inhibitors. Also, it is a lead compound to overcome Fibronectin EDA induced metastatic progression in lung carcinoma cells.

Definition

ChEBI: A hydroxyisoflavone that is isoflavone substituted by hydroxy groups at positions 5, 7 and 3' and methoxy groups at positions 6, 4' and 5' respectively.

target

COX | NOS | NAD(P)H:quinone reductase | α-glucosidase | NO | PGE | p65 | NF-κB

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