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taraxerol

Basic information Safety Supplier Related

taraxerol Basic information

Product Name:
taraxerol
Synonyms:
  • Alnulin
  • D-Friedoolean-14-en-3β-ol
  • Skimmiol
  • Tiliadin
  • (3β)-D-Friedoolean-14-en-3-ol
  • (3β13α)-13-Methyl-27-norolean-14-en-3-ol
  • 3β-Taraxerol
  • Taraxero
CAS:
127-22-0
MF:
C30H50O
MW:
426.73
Mol File:
127-22-0.mol
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taraxerol Chemical Properties

Melting point:
282-285°
Boiling point:
490.7±44.0 °C(Predicted)
Density 
1.01±0.1 g/cm3(Predicted)
storage temp. 
4°C, protect from light
solubility 
≥ 40 mg/mL in DMSO
pka
15.19±0.70(Predicted)
form 
Solid
color 
White
Water Solubility 
insoluble in water
LogP
11.060 (est)
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Safety Information

WGK Germany 
3
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taraxerol Usage And Synthesis

Chemical Properties

White crystalline powder, soluble in organic solvents such as methanol, ethanol, and DMSO, derived from Aster tataricus, Bambusa chinensis, and Taraxacum officinale.

Uses

β-Taraxerol has potential application against novel coronavirus SARS-?CoV-?2, in silico approach to assess the inhibitory potential.

Definition

ChEBI: A pentacyclic triterpenoid that is oleanan-3-ol lacking the methyl group at position 14, with an alpha-methyl substituent at position 13 and a double bond between positions 14 and 15.

in vivo

Taraxerol (5 and 10mg/kg; i.p.) attenuates carrageenan induced paw edema. The effect of taraxerol at the dose of 5mg/kg is found to be significant (p<0.05) only after 4h of carrageenan treatment[2].

target

NO | PGE | TNF-α | IL Receptor | NF-kB | TGF-β/Smad | Akt

taraxerolSupplier

Chembest Research Laboratories Limited
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BioBioPha Co., Ltd.
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Chengdu Biopurify Phytochemicals Ltd.
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S.Z. PhyStandard Bio-Tech. Co., Ltd.
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