Basic information Safety Supplier Related

ETHYL 4-CHLORO-3-TRIFLUOROMETHYLCARBANILATE

Basic information Safety Supplier Related

ETHYL 4-CHLORO-3-TRIFLUOROMETHYLCARBANILATE Basic information

Product Name:
ETHYL 4-CHLORO-3-TRIFLUOROMETHYLCARBANILATE
Synonyms:
  • ETHYL 4-CHLORO-3-TRIFLUOROMETHYLCARBANILATE
  • TIMTEC-BB SBB008265
  • Ethyl 4-chloro-3-(trifluoromethyl)phenylcarbamate
  • Sorafenib related coMpound 2
  • Sorafenib impurity 1/ethyl (4-chloro-3-(trifluoromethyl)phenyl)carbamate
  • N-[4-chloro-3-(trifluoromethyl)phenyl]carbamic acid ethyl ester
  • Regorafenib Ethyl Carbamate Impurity
  • Regorafenib Impurity 39
CAS:
18585-06-3
MF:
C10H9ClF3NO2
MW:
267.63
Mol File:
18585-06-3.mol
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ETHYL 4-CHLORO-3-TRIFLUOROMETHYLCARBANILATE Chemical Properties

Boiling point:
252.5±40.0 °C(Predicted)
Density 
1.402±0.06 g/cm3(Predicted)
solubility 
Chloroform (Slightly), Methanol (Slightly)
pka
12.44±0.70(Predicted)
form 
Solid
color 
White to Off-White
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ETHYL 4-CHLORO-3-TRIFLUOROMETHYLCARBANILATE Usage And Synthesis

Uses

Ethyl (4-Chloro-3-(trifluoromethyl)phenyl)carbamate is an impurity of Sorafenib (S676850); a multiple kinase inhibitor targeting both RAF and receptor tyrosine kinases that promote angiogenesis. Also antineoplastic.

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