Sorafenib related coMpound 8 Chemical Properties

Boiling point:

520.0±50.0 °C(Predicted)

Density 

1.454±0.06 g/cm3(Predicted)

storage temp. 

2-8°C

solubility 

DMSO (Slightly), Methanol (Slightly)

form 

Solid

pka

12.84±0.70(Predicted)

color 

White to Pale Yellow

Major Application

pharmaceutical

InChI

1S/C21H16ClF3N4O3/c1-26-19(30)17-11-14(9-10-27-17)32-13-7-5-12(6-8-13)28-20(31)29-16-4-2-3-15(18(16)22)21(23,24)25/h2-11H,1H3,(H,26,30)(H2,28,29,31)

InChIKey

JWAKXXCHFJSKRN-UHFFFAOYSA-N

SMILES

FC(F)(F)c1c(c(ccc1)NC(=O)Nc2ccc(cc2)Oc3cc(ncc3)C(=O)NC)Cl

Safety Information

WGK Germany 

WGK 3

HS Code 

2933399090

Storage Class

6.1C - Combustible acute toxic Cat.3
toxic compounds or compounds which causing chronic effects

Hazard Classifications

Aquatic Acute 1
Aquatic Chronic 1
Lact.
Repr. 1B
STOT RE 1

Sorafenib related coMpound 8 Usage And Synthesis

Uses

4-Deschloro-2-chloro-Sorafenib is a derivative of Sorafenib (S676850), a multiple kinase inhibitor targeting both RAF kinase and receptor tyrosine kinases that promote angiogensis. Antineoplastic.

Sorafenib related coMpound 8(1431697-81-2)Related Product Information

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