Basic information Safety Supplier Related

3-Fluoro-4-methoxyaniline

Basic information Safety Supplier Related

3-Fluoro-4-methoxyaniline Basic information

Product Name:
3-Fluoro-4-methoxyaniline
Synonyms:
  • 4-AMINO-2-FLUOROANISOLE
  • 3-Fluoro-p-anisidine (NH2=1)
  • 3-FLUORO-P-ANISIDINE
  • 3-FLUORO-4-ANISIDINE
  • 3-FLUORO-4-METHOXYANILINE
  • 3-Fluoro-4-Methoxyaniline 2-Fluoro-4-Aminoanisole
  • 4-Amino-2-fluoroanisol
  • 3-Fluoro-4-methoxy-phenylamine
CAS:
366-99-4
MF:
C7H8FNO
MW:
141.14
EINECS:
627-615-2
Product Categories:
  • Anilines, Amides & Amines
  • Anisoles, Alkyloxy Compounds & Phenylacetates
  • Anilines, Aromatic Amines and Nitro Compounds
  • Aniline
  • Miscellaneous
  • Fluorine Compounds
  • Other fluorin-contained compounds
  • bc0001
Mol File:
366-99-4.mol
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3-Fluoro-4-methoxyaniline Chemical Properties

Melting point:
81-83 °C (lit.)
Boiling point:
135 °C/18 mmHg (lit.)
Density 
1.1382 (estimate)
Flash point:
>110°C
storage temp. 
Keep in dark place,Sealed in dry,Room Temperature
solubility 
Chloroform (Slightly), Methanol (Slightly)
pka
4.18±0.10(Predicted)
form 
Crystalline Powder
color 
Light beige to yellow-brown
BRN 
2717083
CAS DataBase Reference
366-99-4(CAS DataBase Reference)
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Safety Information

Hazard Codes 
Xn,Xi,T
Risk Statements 
20/21/22-36/37/38-23/24/25
Safety Statements 
26-37/39-45-38-36/37/39-28A
RIDADR 
UN2811
WGK Germany 
3
Hazard Note 
Irritant
HazardClass 
6.1
PackingGroup 
III
HS Code 
29214200

MSDS

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3-Fluoro-4-methoxyaniline Usage And Synthesis

Chemical Properties

light beige to yellow-brown crystalline powder

Uses

3-Fluoro-4-methoxyaniline was used as a reagent in the synthesis of novel leucine ureido derivatives which have potent inhibitory activity againt aminopeptidase N. Also used in the synthesis of novel mGluR1 antagonists for the treatment of chronic pain.

General Description

Arrhenius parameter has been measured for the reactions of 3-fluoro-p-anisidine (3-fluoro-4-methoxyaniline) with picryl chloride.

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