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2,3-dimethyl-2H-indazol-6-amine hydrochloride

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2,3-dimethyl-2H-indazol-6-amine hydrochloride Basic information

Product Name:
2,3-dimethyl-2H-indazol-6-amine hydrochloride
Synonyms:
  • 2,3-dimethyl-2H-indazol-6-amine hydrochloride
  • 2,3-Dimethyl-2H-indazol-6-amine monohydrochloride
  • 2,3-Dimethyl-6-amino-2H-indazole hydrochloride
  • 2H-Indazol-6-aMine,2,3-diMethyl-, hydrochloride (1:1)
  • 3-Methyl-6-nitro-1H-indazole hydrochloride
  • 6-amino-2,3-dimethylindazole hydrochloride
  • Pazopanib Impurity 21
  • PAZ20
CAS:
635702-60-2
MF:
C9H12ClN3
MW:
197.66468
EINECS:
200-001-8
Mol File:
635702-60-2.mol
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2,3-dimethyl-2H-indazol-6-amine hydrochloride Chemical Properties

Melting point:
>230°C (dec.)
storage temp. 
Inert atmosphere,Room Temperature
solubility 
DMSO (Slightly), Methanol (Slightly)
form 
Solid
color 
Pale Beige to Light Beige
Stability:
Hygroscopic
InChI
InChI=1S/C9H11N3.ClH/c1-6-8-4-3-7(10)5-9(8)11-12(6)2;/h3-5H,10H2,1-2H3;1H
InChIKey
DYTQJZDNKWQSLS-UHFFFAOYSA-N
SMILES
N1=C2C(C=CC(N)=C2)=C(C)N1C.[H]Cl
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2,3-dimethyl-2H-indazol-6-amine hydrochloride Usage And Synthesis

Description

2,3-dimethyl-2H-indazol-6-amine hydrochloride is a pharmaceutical intermediate impurity, a by-product from the preparation of pazopanib hydrochloride, which can be used as an impurity standard solution for experimental analysis.

Chemical Properties

Powder

Uses

2,3-Dimethyl-6-amino-2H-indazole is an impurity in the synthesis of Pazopanib (P210925) hydrochloride, an oral angiogenesis inhibitor targeting VEGFR and PDGFR.

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