DIETHYL TERT-BUTYLMALONATE Chemical Properties

Boiling point:

102-104 °C/11 mmHg (lit.)

Density 

1.014 g/mL at 25 °C (lit.)

refractive index 

n20/D 1.425(lit.)

Flash point:

195 °F

pka

13.74±0.46(Predicted)

Water Solubility 

Immiscible with water.

BRN 

1781709

Safety Information

Safety Statements 

23-24/25

WGK Germany 

3

MSDS

• Language:English Provider:SigmaAldrich
• Language:English Provider:ALFA

DIETHYL TERT-BUTYLMALONATE Usage And Synthesis

Uses

Diethyl tert-butylmalonate is used in the preparation of enantiomers of 4-tert-butyl-3-isopropyl-2,6,7-trioxa-1-phosphabicyclo[2.2.2]octane 1-sulfide.

Purification Methods

Dissolve it in Et2O, wash with aqueous NaHCO3, H2O, dry (MgSO4), filter, evaporate and distil the residue. Identify by hydrolysis to the acid and determine the neutralisation equivalent (theor: 80.0). The acid has m 155-157o effervescence [Hauser et al. J Am Chem Soc 64 2715 1942, Bush & Beauchamp J Am Chem Soc 75 2949 1953]. [Beilstein 2 IV 2027.]

DIETHYL TERT-BUTYLMALONATE(759-24-0)Related Product Information

• 2-Methylpropanedioic acid
• DIETHYL ISOPROPYLMALONATE
• Ethyl isovalerate
• Diethyl methylmalonate
• ETHYLMALONIC ACID
• ETHYL TERT-BUTYLACETATE
• METHYL TERT-BUTYLACETATE
• Dimethyl isopropylmalonate
• DIMETHYL TERT-BUTYLMALONATE
• Diethyl ethylmalonate
• 2-TERT-BUTYLPROPANE-1,3-DIOL
• (R)-(-)-3-HYDROXY-2-METHYLPROPIONIC ACID METHYL ESTER
• DIETHYL TERT-BUTYLMALONATE
• 3,3-DIMETHYL-1-BUTANOL
• (R)-2-Hydroxymethylbutanoic acid
• 3,3-Dimethylbutyric acid
• METHYL (S)-(+)-3-HYDROXY-2-METHYLPROPIONATE
• Dimethyl methylmalonate