HydroxyMethylidene thione Chemical Properties

Boiling point:

439.4±55.0 °C(Predicted)

Density 

1.34±0.1 g/cm3(Predicted)

pka

4.35±0.40(Predicted)

InChI

InChI=1S/C15H18N4OS/c1-18-6-8-19(9-7-18)14-11(10-20)15(21)17-13-5-3-2-4-12(13)16-14/h2-5,10,20H,6-9H2,1H3,(H,17,21)

InChIKey

AHLVAHJPLRKOQZ-UHFFFAOYSA-N

SMILES

N1C2=CC=CC=C2N=C(N2CCN(C)CC2)C(=CO)C1=S

HydroxyMethylidene thione Usage And Synthesis

Uses

A degradation product of Olanzapine (LY170053) (O253750) in solid oral formulations. Olanzapine impurity.

HydroxyMethylidene thione(1320360-86-8)Related Product Information

• 5,10-Dihydro-2-methyl-4H-thieno[2,3-β][1,5]benzodiazepin-4-one (Olanzapine Impurity)
• 2-Methyl-4-(1-piperazinyl)-10H-thienol[2,3-b][1,5]benzodiazepine
• Olanzapine ThiolactaM IMpurity
• 2-Amino-5-methyl-3-thiophenecarbonitrile
• 2-Propylidenepropanedinitrile
• Olanzapine
• 4-Amino-2-methyl-10H-thiene[2,3-b][1,5]benzodiazepine hydrochloride
• 1-(ChloroMethyl)-1-Methyl-4-(2-Methyl-10H-thieno[2,3-b][1,5]benzodiazepin-4-yl)-piperaziniuM Chloride
• (E)-1-(4-(2-Methyl-10H-benzo[b]thieno[2,3-e][1,4]diazepin-4-yl)piperazin-1-yl)ethanone
• Olanzapine ThioacetoxyMethylidene IMpurity Discontinued
• 2-(1,2-PhenylenediaMino)-5-Methylthiphene-3-carbonitrile
• 1-Fluoro-2-nitrobenzene
• 1-Methylpiperazine
• Olanzapine LactaM IMpurity
• OLANZAPINE N-OXIDE
• 5-Methyl-2-[(2-nitrophenyl)amino]thiophene-3-carbonitrile
• Olanzapine Impurity(ADP-2b)
• Olanzapine dimer