Basic information Safety Supplier Related

tert-Butyl 3-[2-(2-{2-[2-(2-tert-butoxycarbonylethoxy)ethoxy]ethoxy}ethoxy) -ethoxy]propionate

Basic information Safety Supplier Related

tert-Butyl 3-[2-(2-{2-[2-(2-tert-butoxycarbonylethoxy)ethoxy]ethoxy}ethoxy) -ethoxy]propionate Basic information

Product Name:
tert-Butyl 3-[2-(2-{2-[2-(2-tert-butoxycarbonylethoxy)ethoxy]ethoxy}ethoxy) -ethoxy]propionate
Synonyms:
  • tert-Butyl 3-[2-(2-{2-[2-(2-tert-butoxycarbonylethoxy)ethoxy]ethoxy}ethoxy) -ethoxy]propionate
  • OtBu-PEG5-OtBu
  • CH2CH2COOTBU-PEG5-CH2CH2COOTBU
  • Di-tert-butyl 4,7,10,13,16-pentaoxanonadecane-1,19-dioate
  • CAS_439114-12-2
  • 4,7,10,13,16-Pentaoxanonadecanedioic acid, 1,19-bis(1,1-dimethylethyl) ester
  • 1,19-di-tert-butyl 4,7,10,13,16-pentaoxanonadecanedioate - [AC80023]
  • di-tert-butyl 4,7,10,13,16-pentaoxanonadecanedioate
CAS:
439114-12-2
MF:
C22H42O9
MW:
450.56
Mol File:
439114-12-2.mol
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tert-Butyl 3-[2-(2-{2-[2-(2-tert-butoxycarbonylethoxy)ethoxy]ethoxy}ethoxy) -ethoxy]propionate Chemical Properties

Boiling point:
489.0±40.0 °C(Predicted)
Density 
1.046±0.06 g/cm3(Predicted)
storage temp. 
Storage temp. 2-8°C
form 
Liquid
color 
Colorless to light yellow
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tert-Butyl 3-[2-(2-{2-[2-(2-tert-butoxycarbonylethoxy)ethoxy]ethoxy}ethoxy) -ethoxy]propionate Usage And Synthesis

Uses

Bis-PEG6-t-butyl ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

IC 50

PEGs

References

[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005

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