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2-[(4-Acetylphenyl)methyl]cyclopentan-1-one

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2-[(4-Acetylphenyl)methyl]cyclopentan-1-one Basic information

Product Name:
2-[(4-Acetylphenyl)methyl]cyclopentan-1-one
Synonyms:
  • 2-[(4-Acetylphenyl)methyl]cyclopentan-1-one
  • Loxoprofen Impurity D
  • Loxoprofen Related Compound 3 (2-[(4-Acetylphenyl)methyl]cyclopentan-1-one)
  • Loxoprofen impurity 6/2-[(4-Acetylphenyl)methyl]cyclopentan-1-one
  • Loxoprofen Related Compound 3
  • Reaxys ID: 5935353
  • 2-[4-(2-oxycyclopentylmethyl)-phenyl]methylketone
  • 2-(4-acetylbenzyl)cyclopentan-1-one
CAS:
96824-28-1
MF:
C14H16O2
MW:
216.28
Mol File:
96824-28-1.mol
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2-[(4-Acetylphenyl)methyl]cyclopentan-1-one Chemical Properties

Boiling point:
371.7±25.0 °C(Predicted)
Density 
1.108±0.06 g/cm3(Predicted)
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2-[(4-Acetylphenyl)methyl]cyclopentan-1-one Usage And Synthesis

Uses

2-[(4-Acetylphenyl)methyl]cyclopentan-1-one is a possible metabolite of Loxoprofen (L472900, Na salt), a non-selective nonsteroidal anti-inflammatory drug (NSAID) that has been effective in reducing atherosclerosis in mice by reducing inflammation. It becomes active after metabolism in the body and inhibits the activation of cyclooxygenase.

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