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Loxoprofen sodium

Basic information Safety Supplier Related

Loxoprofen sodium Basic information

Product Name:
Loxoprofen sodium
Synonyms:
  • alpha-methyl-4-((2-oxocyclopentyl)methyl)benzeneacetatesodiumsaltdihydrate
  • benzeneaceticacid,alpha-methyl-4-((2-oxocyclopentyl)methyl)-,sodiumsalt,di
  • cs-600
  • loxoprofensodium(patented-nosupply)
  • Loxoprofen sodium dihydrate, >=99%
  • Sodium 2-(4-((2-oxocyclopentyl)methyl)phenyl)propanoate
  • sodium 2-[4-[(2-oxocyclopentyl)methyl]phenyl]propanoate dihydrate
  • 2-{4-[(2-Oxocyclopentyl)methyl]phenyl}propanoic acid sodium salt
CAS:
80382-23-6
MF:
C15H19NaO3
MW:
270.3
EINECS:
1806241-263-5
Product Categories:
  • Analgesics
  • Aromatics
  • Inhibitors
  • Intermediates & Fine Chemicals
  • Pharmaceuticals
  • Antipyretic analgesics
  • APIS
  • Other APIs
  • 80382-23-6
Mol File:
80382-23-6.mol
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Loxoprofen sodium Chemical Properties

storage temp. 
Inert atmosphere,Room Temperature
solubility 
DMSO: soluble
form 
A solid
InChI
InChI=1S/C15H18O3.Na.H/c1-10(15(17)18)12-7-5-11(6-8-12)9-13-3-2-4-14(13)16;;/h5-8,10,13H,2-4,9H2,1H3,(H,17,18);;
InChIKey
ALZXNWUYLUBHJL-UHFFFAOYSA-N
SMILES
C(C1CCCC1=O)C1C=CC(C(C)C(=O)O)=CC=1.[NaH]
CAS DataBase Reference
80382-23-6(CAS DataBase Reference)
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Loxoprofen sodium Usage And Synthesis

Description

Loxoprofen sodium i s an antiinflammatory/analgesic agent useful in the management of rheumatoid arthritis and related disorders. It is converted in vivo to the corresponding trans-hydroxycyclopentane analog, through which it appears to exert its activity.

Originator

Sankyo (Japan)

Uses

anti-inflammatory

Definition

ChEBI: A hydrate that is the dihydrate form of loxoprofen sodium. The parent acid, loxoprofen, is a prodrug that is rapidly converted to its active trans-alcohol metabolite following oral administration.

brand name

LOXONIN

Mechanism of action

As most NSAIDs, loxoprofen is a non-selective cyclooxygenase inhibitor, and works by reducing the synthesis of prostaglandins from arachidonic acid.

Side effects

Adverse effects include anorexia, nausea, vomiting, bleeding, anemia, diarrhea, and constipation.

Loxoprofen sodiumSupplier

Wuhan Penglei Biological Technology Co., Ltd. Gold
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18672616696
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229092275@qq.com
Beijing ECom Technology Co., Ltd. Gold
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17710328343
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3004011422@qq.com
J & K SCIENTIFIC LTD.
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010-82848833 400-666-7788
Email
jkinfo@jkchemical.com
Chembest Research Laboratories Limited
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021-20908456
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sales@BioChemBest.com
Pure Chemistry Scientific Inc.
Tel
001-857-928-2050 or 1-888-588-9418
Email
sales@chemreagents.com
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