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Dolutegravir Impurity 6
Dolutegravir Impurity 6 Basic information
- Product Name:
- Dolutegravir Impurity 6
- Synonyms:
-
- Dolutegravir Impurity 6
- Dolutegravir RR Isomer
- 2H-Pyrido[1',2':4,5]pyrazino[2,1-b][1,3]oxazine-9-carboxamide, N-[(2,4-difluorophenyl)methyl]-3,4,6,8,12,12a-hexahydro-7-hydroxy-4-methyl-6,8-dioxo-, (4R,12aR)-
- (4R,12aR)-N-(2,4-difluorobenzyl)-7-hydroxy-4-methyl-6,8-dioxo-3,4,6,8,12,12a-hexahydro-2H-pyrido[1',2':4,5]pyrazino[2,1-b][1,3]oxazine-9-carboxamide
- Dolutegravir Impurity 42
- Doultegravirr RR Isomer
- Dolutegravir R,R Freebase / R,R-ISomer
- 4-(3-chlorothiophen-2-yl)-1,3-thiazol-2-amine
- CAS:
- 1357289-29-2
- MF:
- C20H19F2N3O5
- MW:
- 419.38
- Mol File:
- 1357289-29-2.mol
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Dolutegravir Impurity 6 Chemical Properties
- Boiling point:
- 669.0±55.0 °C(Predicted)
- Density
- 1.53±0.1 g/cm3(Predicted)
- pka
- 4.50±1.00(Predicted)
- InChIKey
- RHWKPHLQXYSBKR-MEBBXXQBSA-N
- SMILES
- O1CC[C@@H](C)N2C(=O)C3=C(O)C(=O)C(C(NCC4=CC=C(F)C=C4F)=O)=CN3C[C@@]12[H]
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Dolutegravir Impurity 6 Usage And Synthesis
Uses
Dolutegravir RR Isomer is an isomer of Dolutegravir (D528800), a second generation HIV-1 integrase strand transfer inhibitor. Dolutegravir is currently in Phase III clinical trials for the treatment of HIV infection. Dolutegravir has been shown to potently inhibit HIV replication in cells such as peripheral blood mononuclear cells (PBMCs), MT-4 cells and CIP4 cells infected with a self-inactivating PHIV lentiviral vector.
Dolutegravir Impurity 6Supplier
Aurisco Pharmaceutical (Tianjin) Inc. Gold
- Tel
- 022-59885855
Guangzhou Jiuzhi Pharmaceutical Technology Co., Ltd. Gold
- Tel
- 020-89854820
- sales@jzpharma.cn
Nanjing zehe Pharmaceutical Technology Co., Ltd Gold
- Tel
- 17768115366
- henry124604479@163.com
Daicel Chiral Technologies (China)CO.,LTD
- Tel
- 021-50460086-9 15921403865
- han_yajun@dctc.daicel.com
S.Z. PhyStandard Bio-Tech. Co., Ltd.
- Tel
- 0755-4000505016 13380397412
- 3001272453@qq.com
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