2-[2-(4-Fluorophenyl)-2-oxo-1-phenylethyl]-4-methyl-3-oxo-N-phenylpentanamide CAS#: 125971-96-2

2-[2-(4-Fluorophenyl)-2-oxo-1-phenylethyl]-4-methyl-3-oxo-N-phenylpentanamide Basic information

Product Name:

2-[2-(4-Fluorophenyl)-2-oxo-1-phenylethyl]-4-methyl-3-oxo-N-phenylpentanamide

Synonyms:

M-4
2[2-(4-FLUOROPHENYL)-2-OXO-1-PHENYLETHYL]-4-METHYL-3-OXO-PENTANOIC ACID PHENYLAMIDE
4-FLUORO-ALPHA-(2-METHYL-1-OXOPROPYL-GAMA-OXO)-N,BETA-DIPHENYLBENZENE BUTANEAMIDE
4-FLUORO-ALPHA-[2-METHYL-1-OXOPROPYL-GAMMA(3)-OXO]-N,BETA-DIPHENYLBENZENE BUTANE AMIDE
4-fluoro-alpha-(2-methyl-1-oxopropyl)-gamma-oxo-n,bata-diphenylbenzene butaneamide
4-FLUORO-ALPHA-(2-METHYL-1-OXOPROPYL)-GAMMA-OXO-N, BETA-DIPHENYLBENZENE BUTANAMIDE
4-fluoro-α-(2-methyl-1-oxo-propyl)-γ-oxo-N-β-diphenyl benzene butanamide
(4-fluoro-α-[2-methyl-1-oxopropyl]-γ-oxo-N,β-diphenylbenzene butane amide(M-4)

CAS:

125971-96-2

MF:

C26H24FNO3

MW:

417.47

EINECS:

603-107-6

Product Categories:

INTERMEDIATES OF ATORVASTATIN
Chemical intermediate for Atorvastatin Calcium
INTERMEDIATESOFATORVASTATIN
Aromatices
Intermediates & Fine Chemicals
Pharmaceuticals
(intermediate of atorvastatin)

Mol File:

125971-96-2.mol

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2-[2-(4-Fluorophenyl)-2-oxo-1-phenylethyl]-4-methyl-3-oxo-N-phenylpentanamide Chemical Properties

Melting point:: 196-1980C
Boiling point:: 631.4±55.0 °C(Predicted)
Density: 1.211
storage temp.: Sealed in dry,2-8°C
solubility: Chloroform (Slightly, Heated), DMSO (Slightly, Sonicated), Ethyl Acetate (Slightly)
pka: 11.52±0.59(Predicted)
form: Solid
color: White to Off-White
PH: 6.49 at 25℃ and 13.64g/L
InChI: InChI=1S/C26H24FNO3/c1-17(2)24(29)23(26(31)28-21-11-7-4-8-12-21)22(18-9-5-3-6-10-18)25(30)19-13-15-20(27)16-14-19/h3-17,22-23H,1-2H3,(H,28,31)
InChIKey: SNPBHOICIJUUFB-UHFFFAOYSA-N
SMILES: C(NC1=CC=CC=C1)(=O)C(C(C1=CC=CC=C1)C(C1=CC=C(F)C=C1)=O)C(=O)C(C)C
CAS DataBase Reference: 125971-96-2(CAS DataBase Reference)

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2-[2-(4-Fluorophenyl)-2-oxo-1-phenylethyl]-4-methyl-3-oxo-N-phenylpentanamide Usage And Synthesis

Chemical Properties

White to Off-White Solid

Uses

An Atorvastatin intermediate. Atorvastatin is a selective, competitive HMG-CoA reductase inhibitor. The only drug in its class specfically indicated for lowering both elevated LDL-cholesterol and triglycerides in patients with hypercholesterolemia.

2-[2-(4-Fluorophenyl)-2-oxo-1-phenylethyl]-4-methyl-3-oxo-N-phenylpentanamide Preparation Products And Raw materials

Raw materials

Aniline Benzaldehyde Bromoethane Ethylenediamine beta-Alanine 4-Fluorobenzaldehyde 5-(2-Hydroxyethyl)-4-methylthiazole Methyl isobutyrylacetate

2-[2-(4-Fluorophenyl)-2-oxo-1-phenylethyl]-4-methyl-3-oxo-N-phenylpentanamideSupplier

Henan yu Chen pharmaceutical co., LTD Gold

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Email: yuchenchem@126.com

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