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RUSCOGENIN

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RUSCOGENIN Basic information

Product Name:
RUSCOGENIN
Synonyms:
  • FlebopoM
  • HeModren
  • Rectolander
  • Ruscogenin, froM Ophiopogon japonicus
  • (1B,3B,25R)-SPIROST-5-ENE-1,3-DIOL
  • RUSCOGENIN
  • RUSCOGENINE
  • (25R)-spirost-5-ene-1-beta,3-beta-diol
CAS:
472-11-7
MF:
C27H42O4
MW:
430.63
EINECS:
207-447-2
Product Categories:
  • Miscellaneous Natural Products
  • Heterocycles
  • Inhibitors
  • Intermediates & Fine Chemicals
  • Pharmaceuticals
  • Steroids
  • chemical reagent
  • pharmaceutical intermediate
  • phytochemical
  • reference standards from Chinese medicinal herbs (TCM).
  • standardized herbal extract
Mol File:
472-11-7.mol
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RUSCOGENIN Chemical Properties

Melting point:
198-202℃
Boiling point:
563.1±50.0 °C(Predicted)
Density 
1.18
storage temp. 
-20°C Freezer
solubility 
DMSO (Slightly), Ethanol (Slightly), Methanol (Slightly)
pka
14.56±0.70(Predicted)
form 
Solid
color 
White
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Safety Information

Safety Statements 
24/25
HS Code 
29389090
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RUSCOGENIN Usage And Synthesis

Chemical Properties

White powder

Uses

A major steroidal sapogenin from Radix ophiopogon japonicus with robust anti-inflammatory and anti-thrombotic activities. Studies suggest that it inhibits adhesion of leukocytes to a human umbilical vein endothelial cell line (ECV304) injured by tumor necrosis factor-α (TNF-α) in a concentration-dependent manner.

Definition

ChEBI: Ruscogenin is a triterpenoid.

target

PGE | TNF-α | NF-kB | p65 | NO | NOS | COX | ERK | JNK | Akt | p38MAPK | PKA | cAMP | IL Receptor

RUSCOGENINSupplier

Shanghai Moqi Biological Technology Co., LTD Gold
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021-38218169 13341702378
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J & K SCIENTIFIC LTD.
Tel
010-82848833 400-666-7788
Email
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Chembest Research Laboratories Limited
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+86-21-20908456
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sales@BioChemBest.com
Chemsky（shanghai）International Co.,Ltd.
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021-50135380
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shchemsky@sina.com
Sichuan Kulinan Technology Co., Ltd
Tel
400-1166-196 18981987031
Email
cdhxsj@163.com
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