AURANTIO-OBTUSIN Chemical Properties

Melting point:

265-266 °C

Boiling point:

594.6±50.0 °C(Predicted)

Density 

1.510±0.06 g/cm3(Predicted)

storage temp. 

2-8°C

solubility 

Soluble in chloroform, DMSO and methan

form 

powder

pka

6.32±0.20(Predicted)

color 

Orange

Safety Information

Safety Statements 

24/25

HS Code 

29389090

AURANTIO-OBTUSIN Usage And Synthesis

Description

Aurantioobtusin is an anthraquinone originally isolated from Cassia seeds with diverse biological activities. It inhibits rat lens aldose reductase (RLAR) in vitro (IC₅₀ = 13.6 μM). Aurantioobtusin (10 and 100 μM) activates the aryl hydrocarbon receptor (AhR) in a concentration-dependent manner. It inhibits rat platelet aggregation induced by arachidonic acid (Item Nos. 90010 | 90010.1 | 10006607), ADP, and collagen. Aurantioobtusin induces vasorelaxation in isolated precontracted rat mesenteric artery rings, an effect that is inhibited by the PI3K inhibitor LY290042 or inhibition of endothelial nitric oxide synthase (eNOS). It is larvicidal against A. gambiae mosquitoes (LD₅₀ = 10 ppm).

Uses

A compound found in herbal remedies, believed to have an effect on blood platelet aggregation and lower blood lipid count

Definition

ChEBI: A trihydroxyanthraquinone that is 1,3,7-trihydroxy-9,10-anthraquinone which is by methoxy groups at positions 2 and 8, and by a methyl group at position 6.

AURANTIO-OBTUSIN(67979-25-3)Related Product Information

• DanshenP.E
• Cabbage Extract/Cabbage PE.
• Aloe emodin
• Ferulic Acid
• Luteolin
• RADIX SCUTELLARIAE
• ASTRAGALUS P.E.
• DGL
• Salvia Root P.E Tanshinone IIA 20%
• Periplocoside
• Alkannin
• Cassia seed extract
• Indigo
• Hesperidin
• Esculetin
• Chrysoobtusin
• Brown pigment
• Cranesbill Extract