2-[(1-Naphthyloxy)methyl]oxirane
2-[(1-Naphthyloxy)methyl]oxirane Basic information
- Product Name:
- 2-[(1-Naphthyloxy)methyl]oxirane
- Synonyms:
-
- NAPHTHYL GLYCIDYL ETHER
- 1-(2,3-epoxypropoxy)-naphthalen
- 1-naphthylglycidylether
- Propranolol PEP2 Std
- Propranolol Impurity 7
- (2S)-2-(1-naphthalenyloxymethyl)oxirane
- Product NaMe 1-Naphthol Glycidyl Ether 3-(1-Naphthy...
- ether,2,3-epoxypropyl1-naphthyl
- CAS:
- 2461-42-9
- MF:
- C13H12O2
- MW:
- 200.23
- EINECS:
- 219-555-7
- Product Categories:
-
- Intermediates
- Aromatics Compounds
- Aromatics
- Heterocycles
- Mol File:
- 2461-42-9.mol
2-[(1-Naphthyloxy)methyl]oxirane Chemical Properties
- Melting point:
- 95 °C
- Boiling point:
- 163-167
- Density
- 1.192±0.06 g/cm3(Predicted)
- storage temp.
- Refrigerator
- solubility
- Chloroform (Slightly), Ethyl Acetate (Slightly)
- form
- Oil
- color
- Clear Light Yellow
- CAS DataBase Reference
- 2461-42-9(CAS DataBase Reference)
2-[(1-Naphthyloxy)methyl]oxirane Usage And Synthesis
Description
Glycidyl ethers are used as reactive diluents for epoxy resins. Alpha-naphtyl glycidyl ether is formed by adding epichlorhydrin and sodium hydroxide to alpha-naphtol. Contact dermatitis was reported in workers of a chemical plant.
Chemical Properties
2-[(1-Naphthyloxy)methyl]oxirane is Light Purple Oil
Uses
2-[(1-Naphthyloxy)methyl]oxirane is used in the preparation of Naftopidil (N213500) and propranolol (P831800).
Contact allergens
Glycidyl ethers are used as reactive diluents for epoxy resins. Alpha-naphthyl glycidyl ether is formed by adding epichlorhydrin and NaOH to alpha-naphthol. Contact dermatitis was reported in workers of a chemical plant.
Synthesis
The α-naphthol and epichlorohydrin are heated and reacted, and after etherification, 1-chloro-3-(1-naphthyloxy)-2-propanol is generated, and then hydrogen chloride is removed under the action of sodium hydroxide to obtain 2-[ (1-Naphthyloxy)methyl]oxirane.
2-[(1-Naphthyloxy)methyl]oxirane Preparation Products And Raw materials
Raw materials
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