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3-Acetylthiophene

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3-Acetylthiophene Basic information

Product Name:
3-Acetylthiophene
Synonyms:
  • 1-(Thien-3-yl)ethan-1-one, 1-Oxo-1-(thien-3-yl)ethane
  • 3-Acetylthioph
  • Ethanone,1-(3-thienyl)-
  • Ketone, methyl 3-thienyl
  • Ketone,methyl3-thienyl
  • Acetylthiophene,95%
  • Acetylthiophene,97%
  • 3-Acetylthiophene99%
CAS:
1468-83-3
MF:
C6H6OS
MW:
126.18
EINECS:
215-996-4
Product Categories:
  • Building Blocks
  • C4 to C6
  • Sulphur Derivatives
  • Thiophene&Benzothiophene
  • Chemical Synthesis
  • Heterocyclic Building Blocks
  • Thiophenes
  • Heterocyclic Compounds
Mol File:
1468-83-3.mol
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3-Acetylthiophene Chemical Properties

Melting point:
57-62 °C (lit.)
Boiling point:
208-210 °C/748 mmHg (lit.)
Density 
1.176 (estimate)
refractive index 
1.5667 (estimate)
Flash point:
208-210°C
storage temp. 
Keep in dark place,Sealed in dry,Room Temperature
solubility 
Chloroform, Hexane (Slightly)
form 
Adhering Crystals
color 
Beige to light brown
Sensitive 
Light Sensitive
BRN 
107241
InChIKey
RNIDWJDZNNVFDY-UHFFFAOYSA-N
LogP
1.240
CAS DataBase Reference
1468-83-3(CAS DataBase Reference)
NIST Chemistry Reference
Ethanone, 1-(3-thienyl)-(1468-83-3)
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Safety Information

Hazard Codes 
Xn,Xi
Risk Statements 
20/21/22-36/37/38
Safety Statements 
22-24/25-36/37-36-26
RIDADR 
UN2811
WGK Germany 
3
Hazard Note 
Irritant
HazardClass 
6.1
PackingGroup 
III
HS Code 
29349990

MSDS

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3-Acetylthiophene Usage And Synthesis

Chemical Properties

white to light yellow crystal powder

Uses

3-Acetylthiophene was used in the preparation of 1-(methylthiophenylidine)-8-naphthylamine(Schiff′s base) and 1-(thiophen-3-yl)ethanone.

Definition

ChEBI: 3-Acetylthiophene is an aromatic ketone.

General Description

3-Acetylthiophene modified glassy carbon electrode has been used in voltammetric determination of uric acid in urine samples.

Purification Methods

Recrystallise the thiophene from pet ether (b 30-60o) or EtOH. The 2,4-dinitrophenylhydrazone crystallises from CHCl3, m 265o, and the semicarbazone crystallises from EtOH, m 174-175o. [Campaigne & Le Suer J Am Chem Soc 70 1555 1948, Beilstein 17/9 V 399.]

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