(1S)-4, 5-dimethoxyl-1 -(ethoxycarbonyl aminomethyl) -benzocyclobutane Chemical Properties

Boiling point:

406.3±45.0 °C(Predicted)

Density 

1.145±0.06 g/cm3(Predicted)

solubility 

soluble in Chloroform, Dichloromethane, Ethyl Acetate, Methanol

pka

12.42±0.46(Predicted)

(1S)-4, 5-dimethoxyl-1 -(ethoxycarbonyl aminomethyl) -benzocyclobutane Usage And Synthesis

Uses

[[(7S)-3,4-Dimethoxybicyclo[4.2.0]octa-1,3,5-trien-7-yl]methyl]-carbamic Acid Ethyl Ester is an intermediate in the synthesis of ent-Ivabradine Hydrochloride (I940505), which is the enantiomer of Ivabradine Hydrochloride (I940500); a selective bradycardic agent with direct effect on the pacemaker If current of the sinoatrial node. Also an antianginal.

(1S)-4, 5-dimethoxyl-1 -(ethoxycarbonyl aminomethyl) -benzocyclobutane(869856-10-0)Related Product Information

• Ivabradine Impurity 5
• 3-(3-hydroxypropyl)-7,8-dimethoxy-1,3-dihydro-2H-benzo[d]azepin-2-one
• (3,4-Dimethoxybicyclo[4.2.0]octa-1,3,5-trien-7-yl)methanamine hydrochloride
• Ivabradine IMpurity
• 7-DeMethyl Ivabradine
• 7,8-Dimethoxy-1,3-dihydro-2H-3-benzazepin-2-one
• 2H-3-Benzazepin-2-one, 3-[3-[[[(7R)-3,4-dimethoxybicyclo[4.2.0]octa-1,3,5-trien-7-yl]methyl]methylamino]propyl]-1,3-dihydro-7,8-dimethoxy-, ethanedioate (1:1)
• Ivabradine impurity (Br)
• Ivabradine Impurity 1 Hydrochloride
• 1616710-52-1
• Ivabradine Impurity 1 Hydrochloride
• INDEX NAME NOT YET ASSIGNED
• 1204612-29-2
• Dehydro Ivabradine Oxalate
• (Z)-3-(3-chloropropyl)-7,8-diethyl-1H-benzo[d] azepin-2 (3H)-one