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RHAPONTIN

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RHAPONTIN Basic information

Product Name:
RHAPONTIN
Synonyms:
  • 3,3',5-TRIHYDROXY-4'-METHOXY-STILBENE 3-O-BETA-D-GLUCOSIDE
  • 4'-METHOXY-3,3',5-STILBENETRIOL-3-GLUCOSIDE
  • 4'-METHOXY-3,3',5-STILBENETROL
  • 3-hydroxy-5-[2-(3-hydroxy-4-methoxyphenyl)vinyl]phenyl-beta-D-glucopyranoside
  • RHAPONTICIN
  • RHAPONTIN
  • RHAPONTIN FROM RHUBARB ROOT
  • RHAPONTIN WITH HPLC
CAS:
155-58-8
MF:
C21H24O9
MW:
420.41
EINECS:
205-845-0
Product Categories:
  • Miscellaneous Natural Products
  • Cardioglycosides & Glycosides
Mol File:
155-58-8.mol
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RHAPONTIN Chemical Properties

Melting point:
236-240 °C
alpha 
D32 -59.5° (acetone)
Boiling point:
457.61°C (rough estimate)
Density 
1.2828 (rough estimate)
refractive index 
1.6230 (estimate)
storage temp. 
2-8°C
solubility 
Acetone (Slightly), DMSO (Slightly), Methanol (Slightly)
pka
9.16±0.10(Predicted)
form 
Solid
color 
Brown
Water Solubility 
slightly soluble in water
Merck 
13,8258
Stability:
Hygroscopic
InChIKey
GKAJCVFOJGXVIA-DXKBKAGUSA-N
LogP
0.680 (est)
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Safety Information

Hazard Codes 
Xi
Risk Statements 
36/38
Safety Statements 
24/25-37/39-26
WGK Germany 
3
HS Code 
29389090

MSDS

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RHAPONTIN Usage And Synthesis

Chemical Properties

light beige powder

Uses

Rhapontin is a stilbene derivative found in Rheum. It is an inhibitor of Tyrosinase which is responsible for the molting process in insects, undesirable browning of fruits and vegetables, and coloring of skin, hair, and eyes in animals.

Definition

ChEBI: Trans-rhaponticin is a rhaponticin in which the double bond adopts a trans-configuration. It possesses a range of pharmacological activities including antitumour, antiinflammatory, antilipemic and neuroprotective activities. It has a role as an anti-inflammatory agent, a plant metabolite, a neuroprotective agent, an EC 2.3.1.85 (fatty acid synthase) inhibitor, an antineoplastic agent, an apoptosis inducer, an angiogenesis inhibitor, a hypoglycemic agent, an anti-allergic agent and an antilipemic drug.

target

LDL

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