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Hydrocortisone 21-hemisuccinate

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Hydrocortisone 21-hemisuccinate Basic information

Product Name:
Hydrocortisone 21-hemisuccinate
Synonyms:
  • 4-[2-[(8S,9S,10R,11S,13S,14S,17R)-11,17-dihydroxy-10,13-dimethyl-3-oxo-2,6,7,8,9,11,12,14,15,16-decahydro-1H-cyclopenta[a]phenanthren-17-yl]-2-oxoethoxy]-4-oxobutanoic acid
  • hydrocortisone 21-(hydrogen succinate)
  • hydrocortisone 21-hemisuccinate*free acid
  • 11β,17α,21-trihydroxy-4-pregnene-3,20-dione 21-hemisuccinate
  • HYDROCORTISONEHEMISUCCINATE(ANHYDROUS)
  • Cortisol, 21-(hydrogen succinate) (8CI)
  • Cortisol, hydrogen succinate (7CI)
  • NSC 7576
CAS:
2203-97-6
MF:
C25H34O8
MW:
462.53
EINECS:
218-612-3
Product Categories:
  • Steroid and Hormone
  • Steroids
  • APIs
Mol File:
2203-97-6.mol
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Hydrocortisone 21-hemisuccinate Chemical Properties

Melting point:
170~172℃
alpha 
[α]D20 +147~+153° (c=1, C2H5OH) (After Drying)
Boiling point:
685.5±55.0 °C(Predicted)
Density 
1.33±0.1 g/cm3(Predicted)
storage temp. 
−20°C
solubility 
Practically insoluble in water, freely soluble in acetone and in anhydrous ethanol. It dissolves in dilute solutions of alkali carbonates and alkali hydroxides.
form 
Solid
pka
pKa 5.10/5.64(20% aq EtOH/50% aq EtOH) (Uncertain)
color 
White to Off-White
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Safety Information

Safety Statements 
22-24/25
WGK Germany 
3
RTECS 
TU5010147

MSDS

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Hydrocortisone 21-hemisuccinate Usage And Synthesis

Chemical Properties

White or almost white, hygroscopic powder

Uses

Hydrocortisone 21-hemisuccinate is a corticosteroid used as an analytical and chromatography reagent.

Uses

glucocorticoid

Definition

ChEBI: A derivative of succinic acid in which one of the carboxy groups is esterified by the C-21 hydroxy group of cortisol (hydrocortisone).

brand name

A-Hydrocort (Abbott); A-Hydrocort (Hospira); Solu-Cortef (Pharmacia & Upjohn).

Hydrocortisone 21-hemisuccinateSupplier

Chembest Research Laboratories Limited
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