Basic information Safety Supplier Related

C2 DIHYDROCERAMIDE

Basic information Safety Supplier Related

C2 DIHYDROCERAMIDE Basic information

Product Name:
C2 DIHYDROCERAMIDE
Synonyms:
  • N-ACETYL DIHYDROSPHINGOSINE
  • D-erythro-1,3-Dihydroxy-2-acetaMidooctadecane
  • D-erythro-2-AcetaMido-1,3-octadecanediol
  • D-erythro-C2-DihydroceraMide
  • N-[(1S,2R)-2-Hydroxy-1-(hydroxyMethyl)heptadecyl]acetaMide
  • C2 Dihydroceramide (d18:0/2:0)
  • N-ACETOYL-D-ERYTHRO-SPHINGANINE;C2 DIHYDROCERAMIDE (D18:0/2:0)
  • D-erythro-Sphingosine, Dihydro-, N-Acetyl- - CAS 13031-64-6 - Calbiochem
CAS:
13031-64-6
MF:
C20H41NO3
MW:
343.54
Product Categories:
  • Mixed Fatty Acids
  • Fatty Acid Derivatives & Lipids
  • Glycerols
  • Inhibitors
  • Protein Kinase Inhibitors and Activators
  • Glycerols, Fatty Acid Derivatives & Lipids
Mol File:
13031-64-6.mol
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C2 DIHYDROCERAMIDE Chemical Properties

Melting point:
118-119°C
Boiling point:
531.8±40.0 °C(Predicted)
Density 
0.953±0.06 g/cm3(Predicted)
storage temp. 
-20°C Freezer
solubility 
Soluble in DMSO (up to 5 mg/ml, with warming).
form 
White solid
pka
14.27±0.20(Predicted)
color 
White
Stability:
Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20° for up to 1 week.
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C2 DIHYDROCERAMIDE Usage And Synthesis

Description

C2 Dihydroceramide (13031-64-6) is a negative control for C2-ceramide (cat.# 10-1181).1,2 Induces autophagy in a variety of cell types.3,4

Chemical Properties

C2 DIHYDROCERAMIDE is White Solid

Uses

C2 DIHYDROCERAMIDE may be used as a negative control for C2 Ceramide

Uses

May be used as a negative control for C2 Ceramide.

Definition

ChEBI: A dihydroceramide in which the ceramide acyl group is specified as acetyl.

References

1) Bielawska et al. (1993) Selectivity of ceramide-mediated biology. Lack of activity of erythro-dihydroceramide; J. Biol. Chem. 268 26226 2) Obeid et al. (1993) Programmed cell death induced by ceramide; Science, 259 1769 3) Jiang et al. (2012) Gamma-tocotrienol induces apoptosis and autophagy in prostate cancer cells by increasing intracellular dihydrosphingosine and dihydroceramide; Int. J. Cancer, 130 685 4) Siddique et al. (2015) Dihydroceramides: From Bit Players to Lead Actors; J. Biol. Chem., 290 15371

C2 DIHYDROCERAMIDESupplier

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