C2 DIHYDROCERAMIDE Chemical Properties

Melting point:

118-119°C

Boiling point:

531.8±40.0 °C(Predicted)

Density 

0.953±0.06 g/cm3(Predicted)

storage temp. 

-20°C Freezer

solubility 

Soluble in DMSO (up to 5 mg/ml, with warming).

form 

White solid

pka

14.27±0.20(Predicted)

color 

White

Stability:

Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20° for up to 1 week.

C2 DIHYDROCERAMIDE Usage And Synthesis

Description

C2 Dihydroceramide (13031-64-6) is a negative control for C2-ceramide (cat.# 10-1181).1,2 Induces autophagy in a variety of cell types.3,4

Chemical Properties

C2 DIHYDROCERAMIDE is White Solid

Uses

C2 DIHYDROCERAMIDE may be used as a negative control for C2 Ceramide

Uses

May be used as a negative control for C2 Ceramide.

Definition

ChEBI: A dihydroceramide in which the ceramide acyl group is specified as acetyl.

References

[1] A. BIELAWSKA. Selectivity of ceramide-mediated biology. Lack of activity of erythro-dihydroceramide.[J]. The Journal of Biological Chemistry, 1993, 54 1: 26226-26232. DOI:10.1016/s0021-9258(19)74304-x
[2] LINA M. OBEID. Programmed Cell Death Induced by Ceramide[J]. Science, 1993, 259 5102. DOI:10.1126/science.8456305
[3] QING JIANG. Gamma-tocotrienol induces apoptosis and autophagy in prostate cancer cells by increasing intracellular dihydrosphingosine and dihydroceramide[J]. International Journal of Cancer, 2011, 130 3: 685-693. DOI:10.1002/ijc.26054
[4] MONOWARUL MOBIN SIDDIQUE. Dihydroceramides: From Bit Players to Lead Actors.[J]. The Journal of Biological Chemistry, 2015, 290 25: 15371-15379. DOI:10.1074/jbc.r115.653204

C2 DIHYDROCERAMIDE(13031-64-6)Related Product Information

• C14 Dihydroceramide
• N-Stearoyl-phytosphingosine
• (2S, 3S, 4R)-2-OCTANOYLIMINO-1,3,4-OCTADECANETRIOL-1-PHOSPHOCHOLINE (SACCHAROMYCES CEREVISIAE)
• C2 DIHYDROCERAMIDE
• N-(6-[(7-NITRO-2-1,3-BENZOXADIAZOL-4-YL)AMINO]CAPROYL)-PHYTOSPHINGOSINE
• C18 Dihydroceramide
• C6 NBD SAFINGOL
• KRN7000
• C16 DIHYDROCERAMIDE
• N-[12-[(7-NITRO-2-1,3-BENZOXADIAZOL-4-YL)AMINO]DODECANOYL]-SPHINGANINE
• C6 DIHYDROCERAMIDE
• C8 DIHYDROCERAMIDE
• N-ACETYL PHYTOSPHINGOSINE, [ACETYL-1-14C]
• N-ACETYL PHYTOSPHINGOSINE-1-PHOSPHATE, [ACETYL-1-14C]
• N-OLEOYL PHYTOSPHINGOSINE, [OLEOYL-1-14C]
• N-OCTANOYL PHYTOSPHINGOSINE-1-PHOSPHATE, [OCTANOYL-1-14C]
• N-OCTANOYL PHYTOSPHINGOSINE, [OCTANOYL-1-14C]
• N-ACETYL-D-ERYTHRO-DIHYDROSPHINGOSINE, [4,5-3H]