MYRISTYL NICOTINATE
MYRISTYL NICOTINATE Basic information
- Product Name:
- MYRISTYL NICOTINATE
- Synonyms:
-
- 3-Pyridinecarboxylic acid, tetradecyl ester
- MYRISTYL NICOTINATE
- etradecylpyridine-3-carboxylate
- 273203-62-6 Tetradecyl nicotinate
- tetradecyl pyridine-3-carboxylate
- Nicotinic acid,ester,inhibit,delivery,Myristyl nicotinate,impairment,Inhibitor,derivative,lipophilic,skin,barrier,prodrug
- Myristyl nicotinate, 10 mM in DMSO
- CAS:
- 273203-62-6
- MF:
- C20H33NO2
- MW:
- 319.48
- Mol File:
- 273203-62-6.mol
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MYRISTYL NICOTINATE Chemical Properties
- Melting point:
- 40.2-40.8 °C
- Boiling point:
- 411.7±18.0 °C(Predicted)
- Density
- 0.953±0.06 g/cm3(Predicted)
- storage temp.
- Sealed in dry,Room Temperature
- solubility
- DMSO: 9.62 mg/mL (30.11 mM)
- form
- Solid
- pka
- 3.19±0.10(Predicted)
- color
- White to yellow
- Cosmetics Ingredients Functions
- HAIR CONDITIONING
SKIN CONDITIONING - LogP
- 7.790 (est)
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MYRISTYL NICOTINATE Usage And Synthesis
Uses
Tetradecyl Nicotinate can be combined with other drugs in the treatment of dermatological conditions.
Synthesis
Myristyl nicotinate was prepared as follows: under nitrogen atmosphere, nicotinoyl chloride was mixed with triethylamine (TEA), dimethylaminopyridine (DMAP) and different streptanols such as myristyl alcohol. The synthesized myristyl nicotinate obtained was separated by silica gel column chromatography and for further purification, it was converted to HCl salt using standard methods. Purity was confirmed by thin layer chromatography and 1H-NMR.
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