Basic information Safety Supplier Related

quinaldopeptin

Basic information Safety Supplier Related

quinaldopeptin Basic information

Product Name:
quinaldopeptin
Synonyms:
  • quinaldopeptin
  • BMY 28662, BU 3845T
  • Quinaldopeptin (9CI)
CAS:
130743-07-6
MF:
C62H78N14O14
MW:
1243.38
Mol File:
130743-07-6.mol
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quinaldopeptin Chemical Properties

Density 
1.45±0.1 g/cm3(Predicted)
storage temp. 
Store at -20°C
solubility 
DMF: soluble; DMSO: soluble; Ethanol: slightly soluble; Methanol: slightly soluble
form 
Yellow powder.
pka
6.91±0.40(Predicted)
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quinaldopeptin Usage And Synthesis

Description

Quinaldopeptin is a quinomycin antibiotic. It is active against a variety of bacteria, including S. pyogenes, S. aureus, C. perfringens, S. faecalis, E. coli, and K. pneumoniae (MICs = 0.2, 0.4, 0.8, 1.6, 3.1, and 6.3 μg/ml, respectively). It is cytotoxic to B16/F10 and Moser cells (IC50s = 0.0008 and 0.04 μg/ml, respectively) and increases survival in a P388 leukemia mouse model. Quinaldopeptin is a bis-intercalator depsipeptide (NPBID) that binds to and intercalates into DNA (Kd = 32 nM).

Uses

Quinaldopeptin is a symmetrical, cyclic decapeptide from an Amycolatopsis sp. that is a bis-intercalator of DNA, exhibiting strong in vitro antimicrobial and cytotoxic activity. Quinaldopeptin significantly prolongs the survival time of mice inoculated with a murine tumour, and also shows weak nematocidal activity. Quinaldopeptin is related to the luzopeptins and sandramycin.

Uses

Quinaldopeptin is a bis-intercalating cyclic peptide antibiotic.

quinaldopeptinSupplier

Shanghai EFE Biological Technology Co., Ltd.
Tel
021-65675885 18964387627
Email
info@efebio.com
Lynnchem
Tel
86-(0)29-85992781 17792393971
Email
info@lynnchem.com
Novachemistry
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44-20819178-90 02081917890
Email
info@novachemistry.com
Shanghai Hongye Biotechnology Co. Ltd
Tel
400-9205774
Email
sales@glpbio.cn
Shenzhen Polymeri Biochemical Technology Co., Ltd.
Tel
+86-400-002-6226 13028896684
Email
sales@rrkchem.com