4-Chlorobutyryl chloride Chemical Properties

Melting point:

-47 °C

Boiling point:

173-174 °C(lit.)

Density 

1.26 g/mL at 25 °C(lit.)

vapor pressure 

3 mm Hg ( 20 °C)

refractive index 

n20/D 1.461(lit.)

Flash point:

163 °F

storage temp. 

Store below +30°C.

solubility 

Chloroform, DMSO (Sparingly), Ethyl Acetate (Slightly)

form 

Liquid

color 

Clear colorless to yellow

explosive limit

5.5-11.7%(V)

Water Solubility 

soluble in diethyl ether, ethanol, slightly soluble in water.

Sensitive 

Moisture Sensitive

BRN 

773860

Stability:

Hygroscopic, Moisture Sensitive

InChIKey

CDIIZULDSLKBKV-UHFFFAOYSA-N

CAS DataBase Reference

4635-59-0(CAS DataBase Reference)

NIST Chemistry Reference

Butanoyl chloride, 4-chloro-(4635-59-0)

EPA Substance Registry System

Butanoyl chloride, 4-chloro- (4635-59-0)

Safety Information

Hazard Codes 

T,C

Risk Statements 

22-23-35

Safety Statements 

26-28-36/37/39-45-28A

RIDADR 

UN 3390 6.1/PG 1

WGK Germany 

1

RTECS 

EM1406000

Autoignition Temperature

824 °F

Hazard Note 

Toxic/Corrosive/Moisture Sensitive

TSCA 

Yes

HazardClass 

6.1

PackingGroup 

II

HS Code 

29159080

Hazardous Substances Data

4635-59-0(Hazardous Substances Data)

MSDS

• Language:English Provider:4-CBC
• Language:English Provider:SigmaAldrich
• Language:English Provider:ACROS
• Language:English Provider:ALFA

4-Chlorobutyryl chloride Usage And Synthesis

Chemical Properties

Clear colorless to yellow liquid

Uses

4-Chlorobutyryl chloride (4-CBCl) is mainly used in the production of pharmaceuticals and agrochemicals. It is used as pyrazinamide intermediate.

Uses

4-Chlorobutyroyl Chloride is used in the preparation of mitosene and mitosane analogs of Mitomycin C (M371900), an antitumor antibiotic. .

Synthesis Reference(s)

Synthesis, p. 538, 1973 DOI: 10.1055/s-1973-22254

Flammability and Explosibility

Non flammable

4-Chlorobutyryl chloride(4635-59-0)Related Product Information

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• Zinc chloride
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