Cetirizine Methyl Ester Chemical Properties

Boiling point:

508.5±45.0 °C(Predicted)

Density 

1.186±0.06 g/cm3(Predicted)

storage temp. 

Refrigerator

form 

Oil

pka

6.41±0.10(Predicted)

color 

Light yellow to yellow

Cetirizine Methyl Ester Usage And Synthesis

Chemical Properties

Pale Yellow Oil

Uses

Cetirizine methyl ester is an impurity of Cetirizine (HY-17042). Cetirizine, a second-generation antihistamine and the carboxylated metabolite of hydroxyzine, is a specific, orally active and long-acting histamine H1-receptor antagonist[1].

References

[1] Do JA, et al. Collision-induced dissociation pathways of H1-antihistamines by electrospray ionization quadrupole time-of-flight mass spectrometry. Arch Pharm Res. 2017 Jun;40(6):736-745. DOI:10.1007/s12272-017-0921-2

Cetirizine Methyl Ester(83881-46-3)Related Product Information

• NA
• Acetic acid, 2-[2-[2-[4-[(4- chlorophenyl)phenylMethyl]-1-piperazinyl]ethoxy]ethoxy]-
• 4-Chlorobenzhydrol
• 1-(Bromophenylmethyl)-4-chlorobenzene
• Levocetirizine
• SNPT-1809279-00-2
• SNPT-1809278-35-0
• (R)-De(carboxyMethyl) Cetirizine Ethanol Dihydrochloride
• 4-Chlorobenzophenone
• 1,4-BIS[(4-CHLOROPHENYL)PHENYLMETHYL]PIPERAZINE DIHYDROCHLORIDE
• rac Cetirizine N-Oxide > 70% by HPLC (Mixture of Diastereomers)
• Cetirizine Glycerol Ester
• Cetirizine Ethyl Ester (USP RC A)
• (RS)-2-[2-[4-[(2-Chloro-phenyl)phenylMethyl]piperazin-1-yl]ethoxy]aceticAcidDihydrochloride
• (S)-Cetirizine Dihydrochloride
• Cetirizine dihydrochloride
• 1-Piperazineethanol,4-[(2-chlorophenyl)(3-chlorophenyl)methyl]-, hydrochloride (1:2)
• iperazineacetic acid, 4-[(4- chlorophenyl)phenylMethyl]-