3-N-BUTYLPHTHALIDE Chemical Properties

Boiling point:

265.75°C (rough estimate)

Density 

1.0527 (rough estimate)

refractive index 

1.5197 (estimate)

FEMA 

3334 | 3-N-BUTYLPHTHALIDE

storage temp. 

Sealed in dry,Store in freezer, under -20°C

solubility 

Chloroform (Slightly), Methanol (Slightly); Almost insoluble in water, soluble in alcohol and oils.

form 

Oil

color 

Colourless to Yellow

Odor

at 10.00 % in dipropylene glycol. herbal phenolic celery

Odor Type

herbal

JECFA Number

1169

Stability:

Hygroscopic

LogP

2.80

NIST Chemistry Reference

3-Butylphthalide(6066-49-5)

EPA Substance Registry System

1(3H)-Isobenzofuranone, 3-butyl- (6066-49-5)

3-N-BUTYLPHTHALIDE Usage And Synthesis

Chemical Properties

3-N-Butylphthalide has a warm, spicy herbaceous odor.

Occurrence

Reported found in Levisticum officinale (lovage) and L. acutilobum; also in celery oil.

Uses

3-Butylphthalide is a cardiovascular drug used for the treatment of cerebral ischemic stroke. This interesting Lactone finds use in the composing of meat flavors, spice blends, etc. 

Preparation

From celery oil; from phthalide via bromination and subsequent reaction of the resulting phthalidic acid with n-butyl magnesium bromide.

Definition

ChEBI: Butylphthalide is a member of benzofurans.

Aroma threshold values

Detection: 5 ppb

3-N-BUTYLPHTHALIDE(6066-49-5)Related Product Information

• Palmitic acid ethyl ester
• Donepezil
• ALUMINUM N-BUTOXIDE
• N-BUTYLETHYLMAGNESIUM
• Decanoic acid
• METHYL NONADECANOATE
• Emamectin
• Homovanillic acid
• Isochlorogenic acid A
• Polypropylenglycol diglycidyl ether
• Cupric acetate monohydrate
• Tetrahydrofuran
• DICHLOFLUANID
• 4-tert-Butyltoluene
• 4'-tert-Butylacetophenone
• Butyldi-1-adamantylphosphine
• Di(1-adamantyl)-n-butylphosphine hydriodide
• n-Propyl Dioxepin