FMOC-12-AMINODODECANOIC ACID Chemical Properties

Melting point:

102 °C

Boiling point:

628.8±28.0 °C(Predicted)

Density 

1.119±0.06 g/cm3(Predicted)

storage temp. 

2-8°C

pka

4.78±0.10(Predicted)

form 

powder

color 

white

BRN 

9593537

Safety Information

Safety Statements 

22-24/25

WGK Germany 

3

FMOC-12-AMINODODECANOIC ACID Usage And Synthesis

Description

Fmoc-12-aminododecanoic acid is an alkane chian with terminal Fmoc-protected amine and carboxylic acid groups. The compound can be used as a PROTAC linker in the synthesis of PROTACs. The Fmoc group can be deprotected under basic condition to obtain the free amine which can be used for further conjugations. The terminal carboxylic acid can react with primary amine groups in the presence of activators (e.g. EDC, or HATU) to form a stable amide bond.

Chemical Properties

White to off-white powder

Uses

12-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)dodecanoic Acid has been used as a reactant for the preparation of pro-apoptotic peptide functionalized gold nanoparticles as a new anti-cancer strategy of damaging mitochondria.

reaction suitability

reaction type: Fmoc solid-phase peptide synthesis

FMOC-12-AMINODODECANOIC ACID(128917-74-8)Related Product Information

• 6-Aminopenicillanic acid
• FMOC-12-AMINODODECANOIC ACID-ALKO RESIN
• 12-(METHYLAMINO)DODECANOIC ACID
• FMOC-12-AMINODODECANOIC ACID
• 12-AMINODODECANOIC ACID