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FMOC-12-AMINODODECANOIC ACID

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FMOC-12-AMINODODECANOIC ACID Basic information

Product Name:
FMOC-12-AMINODODECANOIC ACID
Synonyms:
  • N-(9-FLUORENYLMETHOXYCARBONYL)-12-AMINODODECANOIC ACID
  • N-(9-FLUORENYLMETHOXYCARBONYL)-12-AMINOLAURIC ACID
  • N-(9-FLUORENYLMETHYLOXYCARBONYL)-12-AMINO-DODECANOIC ACID
  • FMOC-12-ADO-OH
  • FMOC-12-AMINODODECANOIC ACID
  • FMOC-12-AMINOLAURIC ACID
  • FMOC-NH-(CH2)11-COOH
  • 12-(FMOC-AMINO)DODECANOIC ACID
CAS:
128917-74-8
MF:
C27H35NO4
MW:
437.57
Product Categories:
  • Amino Acids
Mol File:
128917-74-8.mol
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FMOC-12-AMINODODECANOIC ACID Chemical Properties

Melting point:
102 °C
Boiling point:
628.8±28.0 °C(Predicted)
Density 
1.119±0.06 g/cm3(Predicted)
storage temp. 
2-8°C
pka
4.78±0.10(Predicted)
BRN 
9593537
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Safety Information

Safety Statements 
22-24/25
WGK Germany 
3
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FMOC-12-AMINODODECANOIC ACID Usage And Synthesis

Description

Fmoc-12-aminododecanoic acid is an alkane chian with terminal Fmoc-protected amine and carboxylic acid groups. The compound can be used as a PROTAC linker in the synthesis of PROTACs. The Fmoc group can be deprotected under basic condition to obtain the free amine which can be used for further conjugations. The terminal carboxylic acid can react with primary amine groups in the presence of activators (e.g. EDC, or HATU) to form a stable amide bond.

Chemical Properties

White to off-white powder

Uses

12-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)dodecanoic Acid has been used as a reactant for the preparation of pro-apoptotic peptide functionalized gold nanoparticles as a new anti-cancer strategy of damaging mitochondria.

FMOC-12-AMINODODECANOIC ACIDSupplier

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