2-Cyclopentyl-4-(5-phenyl-1H-pyrrolo[2,3-b]pyridin-3-yl-benzoicacid Chemical Properties

storage temp. 

room temp

solubility 

DMSO: soluble20mg/mL, clear

form 

powder

color 

white to beige

Safety Information

WGK Germany 

3

2-Cyclopentyl-4-(5-phenyl-1H-pyrrolo[2,3-b]pyridin-3-yl-benzoicacid Usage And Synthesis

Uses

GSK-650394 has been used as a serum and glucocorticoid-activated kinase (SGK1) inhibitor.

Definition

ChEBI: 2-cyclopentyl-4-(5-phenyl-1H-pyrrolo[2,3-b]pyridin-3-yl)benzoic acid is a phenylpyridine.

Biochem/physiol Actions

GSK-650394 has an IC50 value of 62?nM for serum and glucocorticoid-activated kinase-1 (SGK1) and 103?nM for SGK2. It has an ability to stop viral replication at concentrations that are nontoxic to cells.

storage

Store at RT

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