2-Desoxy-4-epi-pulchellin Chemical Properties

Melting point:

135 °C

Boiling point:

408.2±45.0 °C(Predicted)

Density 

1.14±0.1 g/cm3(Predicted)

solubility 

Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.

form 

Powder

pka

15.03±0.60(Predicted)

color 

White to off-white

InChI

InChI=1S/C15H22O3/c1-8-6-12-10(9(2)14(17)18-12)7-15(3)11(8)4-5-13(15)16/h8,10-13,16H,2,4-7H2,1,3H3/t8-,10-,11+,12+,13+,15+/m1/s1

InChIKey

BOPADYWRUULRBD-MBICNOSFSA-N

SMILES

O1C(=O)C(=C)[C@@]2([H])C[C@@]3(C)[C@@]([H])(CC[C@@H]3O)[C@H](C)C[C@]12[H]

2-Desoxy-4-epi-pulchellin Usage And Synthesis

Description

2-Desoxy-4-epi-pulchellin has potent in vitro cytotoxicities against the K562, MCF-7, Hela, DU145, U937, H1975, SGC-7901, A549, MOLT-4, and HL60 cell lines with IC50 values ranging from 0.10 to 46.7uM, while it shows significant antiviral (H1N1 and H3N2) activities, it also displays significant antimycobacterial activity (IC50=7.6 uM).

Uses

2-Desoxy-4-epi-pulchellin (compound 13) is a compound isolated from dichloromethane-soluble portion of Polygonum hydropiper[1].

target

Antifection

References

[1] Xiao H, et al. Biological evaluation of phytoconstituents from Polygonum hydropiper. Nat Prod Res. 2017;31(17):2053-2057. DOI:10.1080/14786419.2016.1269094

2-Desoxy-4-epi-pulchellin(122872-03-1)Related Product Information

• beta-Eudesmol
• alpha-Terpineol
• 2-(3,4-Dihydroxyphenyl)-8-(2-O-beta-L-galactopyranosyl-beta-D-glucopyranosyl)-5,7-dihydroxy-4H-1-Benzopyran-4-one
• (4E,6E)-1,7-Diphenyl-4,6-heptadien-3-one
• hydroxygenkwanin
• Artemether
• beta-Sitosterol
• alpha-Cyperone
• MOSLOFLAVONE
• Hydroxyecdysone