ChemicalBook > Product Catalog > Biochemical Engineering > Inhibitors > Cell Cycle > CDK inhibitors > ML167
ML167
ML167 Basic information
- Product Name:
- ML167
- Synonyms:
-
- ML167
- ML167/ML-167
- 5-[4-[[(5-Methyl-2-furanyl)methyl]amino]-6-quinazolinyl]-2-furanmethanol
- CID 44968231
- 5-[4-[[(5-Methyl-2-furanyl)methyl]amino]-6-quinazolinyl]-2-furanmethanol ML167
- NCGC00188654
- (5-(4-(((5-Methylfuran-2-yl)methyl)amino)quinazolin-6-yl)furan-2-yl)methanol
- CID44968231;NCGC00188654
- CAS:
- 1285702-20-6
- MF:
- C19H17N3O3
- MW:
- 335.36
- EINECS:
- 808-432-9
- Product Categories:
-
- Inhibitors
- Mol File:
- 1285702-20-6.mol
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ML167 Chemical Properties
- Boiling point:
- 531.8±45.0 °C(Predicted)
- Density
- 1.335±0.06 g/cm3(Predicted)
- storage temp.
- -20°C
- solubility
- DMSO: soluble10mg/mL, clear
- form
- powder
- pka
- 13.84±0.10(Predicted)
- color
- off-white to gray to brown
- Stability:
- Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20° for up to 3 months.
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ML167 Usage And Synthesis
Description
ML167 (1285702-20-6) is a highly selective cell permeable inhibitor of Cdc2-like kinase 4 (Clk4) – IC50?= 136nM. It displays at least 10-fold greater selectivity over the related kinases Clk1(1.52 μM), Clk2(1.65μM), Clk3(>10μM), Dyrk1A(>10μM), and Dyrk1B(4.4 μM).
Definition
ChEBI: [5-[4-[(5-methyl-2-furanyl)methylamino]-6-quinazolinyl]-2-furanyl]methanol is a member of quinazolines.
target
Clk4
References
1) Rosenthal?et al. (2010),?An inhibitor of the Cdc2-like kinase 4 (Clk4); Probe Reports from the NIH Molecular Libraries Program
ML167Supplier
Nanjing Chemlin Chemical Co., Ltd
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- 025-83697070
- info@chemlin.com.cn
MedChemexpress LLC
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- 021-58955995
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CEG Chemical Science&Technology Co., Ltd.
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- Mobile:13665161512
Shanghai HuanChuan Industry Co.,Ltd.
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- 021-61478794
- sales@hcshhai.com
Hubei Jusheng Technology Co.,Ltd
- Tel
- 027-59599241 18871490274
- 1400878000@qq.com