Basic information Safety Supplier Related

C-(1H-INDOL-5-YL)-METHYLAMINE

Basic information Safety Supplier Related

C-(1H-INDOL-5-YL)-METHYLAMINE Basic information

Product Name:
C-(1H-INDOL-5-YL)-METHYLAMINE
Synonyms:
  • 5-(aminomethyl)-indol
  • INDOLE-5-METHYLAMINE
  • C-(1H-INDOL-5-YL)-METHYLAMINE
  • (1H-INDOL-5-YL)METHANAMINE
  • (1H-Indol-5-yl)methylamine
  • 5-(AMINOMETHYL)INDOLE
  • ((Indol-5-yl)Methyl)aMine
  • 1-(1H-Indol-5-yl)MethanaMine
CAS:
81881-74-5
MF:
C9H10N2
MW:
146.19
Product Categories:
  • Amines
  • Aromatics
  • Heterocycles
  • Inhibitors
  • Intermediates & Fine Chemicals
  • Pharmaceuticals
  • pharmacetical
  • Building Blocks
  • Heterocyclic Building Blocks
  • Indoles
  • Building Blocks
  • C7 to C9
  • Chemical Synthesis
  • Heterocyclic Building Blocks
Mol File:
81881-74-5.mol
More
Less

C-(1H-INDOL-5-YL)-METHYLAMINE Chemical Properties

Melting point:
114-122 °C
Boiling point:
335.6±17.0 °C(Predicted)
Density 
1.199±0.06 g/cm3(Predicted)
storage temp. 
under inert gas (nitrogen or Argon) at 2–8 °C
pka
17.07±0.30(Predicted)
More
Less

Safety Information

Hazard Codes 
Xn
Risk Statements 
22-36/37/38
Safety Statements 
26-36
WGK Germany 
3
RTECS 
NL4461500

MSDS

More
Less

C-(1H-INDOL-5-YL)-METHYLAMINE Usage And Synthesis

Uses

5-(AMinoMethyl)indole has been used as reactant for preparation of:• and HIV-1 integrase inhibitors targeting the catalytic domain and its ability for interaction with LEDGF/p751•

Uses

5-(Aminomethyl)indole is used in the synthesis of Vigabatrin (V253000) bioisosteres as inhibitors of γ-aminobutyric acid aminotransferase (GABA-AT) inhibitors.

Uses

Reactant for preparation of:

  • HIV-1 integrase inhibitors targeting the catalytic domain and its ability for interaction with LEDGF/p75
  • Inhibitors of Gli1-mediated transcription in the Hedgehog pathway
  • SCIO-469-like compounds for the inhibition of p38 MAP kinase
  • 4-(indol-5-ylamino)thieno[2,3-b]pyridine-5-carbonitriles as protein kinase c theta (PKC θ) inhibitors
  • Non-covalent thrombin inhibitors

C-(1H-INDOL-5-YL)-METHYLAMINE Preparation Products And Raw materials

Raw materials

C-(1H-INDOL-5-YL)-METHYLAMINESupplier

J & K SCIENTIFIC LTD.
Tel
010-82848833 400-666-7788
Email
jkinfo@jkchemical.com
BeiJing Hwrk Chemicals Limted
Tel
0757-86329057 18516978288
Email
sales.gd@hwrkchemical.com
Chemsky(shanghai)International Co.,Ltd.
Tel
021-50135380
Email
shchemsky@sina.com
Shanghai AmasPharm Co., Ltd.
Tel
021-34978309 18621091017
Email
sales@amaspharm.com
Wuhan TCASChem Technology Co., Ltd.
Tel
027-86697669 13986148687
Email
947257336@qq.com