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CARBOXYIBUPROFEN

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CARBOXYIBUPROFEN Basic information

Product Name:
CARBOXYIBUPROFEN
Synonyms:
  • 2-[4-(2-Methyl-3-hydroxy-3-oxopropyl)phenyl]propionic acid
  • Ibuprofen Carboxylic Acid
  • 3-[4-(1-Carboxyethyl)phenyl]-2-methylpropionic acid
  • CARBOXYIBUPROFEN
  • IBUPROFEN CARBOXYLIC ACID (MIXTURE OF DIASTERIOMERS)
  • CARBOXYIBUPROFEN (MIXTURE OF STEREOISOMERS)
  • 2,4(2-Carboxypropyl)phenylpropionic Acid
  • 2-[4-(2-Carboxypropyl)phenyl]propionic Acid
CAS:
15935-54-3
MF:
C13H16O4
MW:
236.26
Product Categories:
  • Metabolite Reference Standard
  • Chiral Reagents
  • Intermediates & Fine Chemicals
  • Metabolites & Impurities
  • Pharmaceuticals
Mol File:
15935-54-3.mol
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CARBOXYIBUPROFEN Chemical Properties

Melting point:
114-116°C
Boiling point:
416.2±25.0 °C(Predicted)
Density 
1.211±0.06 g/cm3(Predicted)
storage temp. 
-20°C Freezer
solubility 
Chloroform (Slightly), Ethyl Acetate (Slightly), Methanol (Slightly)
form 
Solid
pka
4.39±0.10(Predicted)
color 
White to Off-White
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CARBOXYIBUPROFEN Usage And Synthesis

Description

Ibuprofen carboxylic acid is a major metabolite of ibuprofen (Item Nos. 70280 | 16793 | 16794). It prevents fructose-, cyanate-, and prednisolone-induced inactivation of catalase and fructose- and cyanate-induced inactivation of fumarase when used at a concentration of 2 mM and penetrates into the lens of isolated bovine eyes. Ibuprofen carboxylic acid has been found in bank filtrate and surface water, as well as influent and effluent wastewater, and is considered a micropollutant.

Chemical Properties

White Solid

Uses

The major metabolite of Ibuprofen; may reduce the risk of cataract by protecting lenticular enzymes.

Definition

ChEBI: A dicarboxylic acid that is ibuprofen in which one of the methyl groups in the isobutyl portion has been converted to the corresponding carboxylic acid.

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