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N-Cbz-L-Phenylalanine

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N-Cbz-L-Phenylalanine Basic information

Product Name:
N-Cbz-L-Phenylalanine
Synonyms:
  • N-benzyloxycarbonyl-L-3-phenylalanine
  • N-CBZ-L-PHENYLALANINE CRYSTALLINE
  • CBZ-L-PHENYLALAINE
  • n-benzyloxycarbonyl-1-phenylalanine
  • N-Carbobenzyloxy-L-phenylalanine, 99+%
  • CBZ-L-PHENYLALANINE-OH
  • CBZ-L-Phe-OH
  • BOC-PHE (N-BENZYLOXYCARBONYL)-L-PHENYLALANINE
CAS:
1161-13-3
MF:
C17H17NO4
MW:
299.32
EINECS:
214-599-3
Product Categories:
  • Phenylalanine [Phe, F]
  • Z-Amino Acids and Derivatives
  • Amino Acids
  • Amino Acids (N-Protected)
  • Biochemistry
  • Cbz-Amino Acids
  • Protected Amino Acids
  • AMINOACIDS DERIVATIVES
  • Amino Acid Derivatives
  • PROTECTED AMINO ACID & PEPTIDES
  • Chiral Compounds
  • Cbz-Amino acid series
Mol File:
1161-13-3.mol
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N-Cbz-L-Phenylalanine Chemical Properties

Melting point:
85-87 °C(lit.)
alpha 
5 º (c=5,acetic acid)
Boiling point:
440.65°C (rough estimate)
Density 
1.1441 (rough estimate)
refractive index 
5.3 ° (C=4, AcOH)
storage temp. 
Keep in dark place,Sealed in dry,Room Temperature
solubility 
DMF (Sparingly), DMSO (Slightly), Methanol (Slightly)
pka
3.86±0.10(Predicted)
form 
Powder
color 
White to off-white
optical activity
[α]20/D +5°, c = 5 in acetic acid
BRN 
2222826
CAS DataBase Reference
1161-13-3(CAS DataBase Reference)
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Safety Information

Hazard Codes 
Xn
Risk Statements 
62-36/37/38-20/21/22
Safety Statements 
22-24/25-36-26
WGK Germany 
3
RTECS 
AY4343000
HS Code 
29242990

MSDS

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N-Cbz-L-Phenylalanine Usage And Synthesis

Chemical Properties

white amorphous powder

Uses

Inhibitor of thermolysin

Uses

N-(Carbobenzyloxy)-L-phenylalanine is used in the synthesis of neurokinin antagonists. Furthermore it is used in the preparation of Co(II), Zn(II), and Cd(II) complexes with N-benzyloxycarbonyl-S-phenylalanine that displays antimicrobial activity against common strains of bacteria.

Uses

N-Cbz-L-Phenylalanine is used in the synthesis of neurokinin antagonists. Furthermore it is used in the preparation of Co(II), Zn(II), and Cd(II) complexes with N-benzyloxycarbonyl-S-phen ylalanine that displays antimicrobial activity against common strains of bacteria.

Biochem/physiol Actions

Inhibitor of thermolysin

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