THERMOLYSIN
THERMOLYSIN Basic information
- Product Name:
- THERMOLYSIN
- Synonyms:
-
- THERMOLYSIN
- THERMOPHILIC-BACTERIAL PROTEASE
- PROTEASE TYPE X
- EC 3.4.24.2
- EC 3.4.24.27
- EC 3.4.24.37
- Thermolysin from Geobacillus stearothermophilus
- Thermolysin Bacillus thermoproteolyticus rokko
- CAS:
- 9073-78-3
- MF:
- NULL
- MW:
- 0
- EINECS:
- 232-973-4
- Mol File:
- Mol File
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THERMOLYSIN Chemical Properties
- storage temp.
- -20°C
- form
- powder
- color
- tan or off-white
- biological source
- Geobacillus stearothermophilus
- Specific Activity
- 30-350units/mg protein (E1%/280)
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Safety Information
- Hazard Codes
- Xn
- Risk Statements
- 36/37/38-42/43
- Safety Statements
- 22-26-36/37
- WGK Germany
- 3
- F
- 3-10-21
MSDS
- Language:English Provider:SigmaAldrich
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THERMOLYSIN Usage And Synthesis
Uses
In studies of protein sequences.
Uses
Thermolysin has been shown to have a prosequeence that acts as an intramolecular chaperone in vivo. It has also been used in a study to investigate the effects of sodium chloride on thermal stability and catalytic activity.
General Description
Thermolysin is a protease that has specificity different from other proteases available for sequence investigations.
in vivo
Thermolysin (50 mg/kg, p.o., once) lowers systolic blood pressure in SHR rats[4].
Thermolysin is not acutely toxic with an oral LD50 of more than 18000 mg/kg in rats and more than 24000 mg/kg in mice (Acute toxicity studies)[5].
| Animal Model: | Spontaneously hypertensive rats (SHR) rats[4] |
| Dosage: | 50 mg/kg |
| Administration: | Oral administration (p.o.), once |
| Result: | Lowered systolic blood pressure in SHR rats, with maximal reduction by 22 mm in systolic blood pressure being observed 6 h after administration. |
THERMOLYSINSupplier
Shanghai Guchen Biotechnology Co., LTD Gold
- Tel
- 021-34675735 19147740836
- 1986399151@qq.com
Amano Enzyme Manufacturing(China),Ltd. Shanghai Branch Gold
- Tel
- 021-6249-0810 13611831109
- lihao_duan@amano-enzyme.com.cn
Hubei wei shi reagent group ltd., company Gold
- Tel
- 027-59105166; 13125137732
- 2853863890@qq.com
Adamas Reagent, Ltd.
- Tel
- 400-6009262 16621234537
- chenyj@titansci.com
Tianjin heowns Biochemical Technology Co., Ltd.
- Tel
- 400 638 7771
- sales@heowns.com
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THERMOLYSIN(9073-78-3)Related Product Information
- Subtilisin
- Trypsin
- Proteinase K
- Urinary Trypsin Inhibitor
- ACHROMOPEPTIDASE
- MG-115
- trysin-chymotrypsin
- Basic protease
- EC 3.4.24.4
- EC 3.4.24.4
- EC 3.4.24.4
- EC 3.4.24.4
- EC 3.4.24.4
- EC 3.4.24.4,THERMOLYSIN,thermolysin(bacillusthermoproteolyticus
- EC 3.4.24.4
- EC 3.4.24.4
- thermolysin (255-316)
- alpha-2-macroglobulin-thermolysin complex