THP-PEG7-OH
THP-PEG7-OH Basic information
- Product Name:
- THP-PEG7-OH
- Synonyms:
-
- THP-PEG7-OH
- 3,6,9,12,15,18-Hexaoxaeicosan-1-ol, 20-[(tetrahydro-2H-pyran-2-yl)oxy]-
- OH-PEG7-THP
- THP-PEG7-OH/3,6,9,12,15,18-Hexaoxaeicosan-1-ol, 20-[(tetrahydro-2H-pyran-2-yl)oxy]-
- 20-((Tetrahydro-2H-pyran-2-yl)oxy)-3,6,9,12,15,18-hexaoxaicosan-1-ol
- CAS:
- 873110-21-5
- MF:
- C19H38O9
- MW:
- 410.5
- Mol File:
- 873110-21-5.mol
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THP-PEG7-OH Chemical Properties
- Boiling point:
- 503.9±50.0 °C(Predicted)
- Density
- 1.11±0.1 g/cm3(Predicted)
- pka
- 14.36±0.10(Predicted)
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THP-PEG7-OH Usage And Synthesis
Biological Activity
THP-PEG7-alcohol is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References
[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562
THP-PEG7-OHSupplier
Borenpharm Co., Ltd
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Amatek Scientific Co. Ltd.
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Shaanxi borno biotechnology co., LTD
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Shanghai Sunway Pharmaceutical Technology Co.,Ltd.
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