5-CHLORO-N-(6-PHENYLHEXYL)-1-NAPHTHALENESULFONAMIDE Chemical Properties

Melting point:

75-76°C

Boiling point:

577.5±52.0 °C(Predicted)

Density 

1.220±0.06 g/cm3(Predicted)

storage temp. 

−20°C

solubility 

Acetonitrile (Slightly), Chloroform (Slightly)

form 

Off-white crystalline solid.

pka

11.25±0.50(Predicted)

color 

Off-White to Pale Yellow

Safety Information

WGK Germany 

3

MSDS

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5-CHLORO-N-(6-PHENYLHEXYL)-1-NAPHTHALENESULFONAMIDE Usage And Synthesis

Chemical Properties

Crystalline Solid

Uses

SC-9 is a PKC activator in the presence of Ca2+[1][2].

Definition

ChEBI: 5-chloro-N-(6-phenylhexyl)-1-naphthalenesulfonamide is a member of naphthalenes and a sulfonic acid derivative.

Biological Activity

A potent activator of protein kinase C.

References

[1] Ito M, et al. N-(6-phenylhexyl)-5-chloro-1-naphthalenesulfonamide, a novel activator of protein kinase C. Biochemistry. 1986 Jul 29;25(15):4179-84. DOI:10.1021/bi00363a002
[2] Nishino H, et al. N-(6-phenylhexyl)-5-chloro-1-naphthalenesulfonamide is one of a new class of activators for Ca2+-activated, phospholipid-dependent protein kinase. Biochim Biophys Acta. 1986 Nov 28;889(2):236-9. DOI:10.1016/0167-4889(86)90109-6

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