Salvianolic acid
Salvianolic acid Basic information
- Product Name:
- Salvianolic acid
- Synonyms:
-
- (2R)-3-(3,4-Dihydroxyphenyl)-2-[(E)-3-[2-[(E)-2-(3,4-dihydroxyphenyl)ethenyl]-3,4-dihydroxyphenyl]prop-2-enoyl]oxypropanoic acid
- SALVIANOLIC ACID A 98.0% BY HPLC
- Danphenolic acid A
- (R)-3-(3,4-Dihydroxyphenyl)-2-(((E)-3-(2-((E)-3,4-dihydroxystyryl)-3,4-dihydroxyphenyl)acryloyl)o
- Salvianolic acid A, froM Salvia Miltiorrhiza
- (R)-3-(3,4-Dihydroxyphenyl)-2-(((E)-3-(2-((E)-3,4-dihydroxystyryl)-3,4-dihydroxyphenyl)acryloyl)oxy)propanoic acid
- (αR)-α-[[(2E)-3-[2-[(1E)-2-(3,4-Dihydroxyphenyl)ethenyl]-3,4-dihydroxyphenyl]-1-oxo-2-propen-1-yl]oxy]-3,4-dihydroxybenzenepropanoic acid
- Dan phenolic acid A hydrate
- CAS:
- 96574-01-5
- MF:
- C26H22O10
- MW:
- 494.45
- Product Categories:
-
- chemical reagent
- pharmaceutical intermediate
- Aromatics
- phytochemical
- reference standards from Chinese medicinal herbs (TCM).
- standardized herbal extract
- Chiral Reagents
- Intermediates & Fine Chemicals
- Pharmaceuticals
- Mol File:
- 96574-01-5.mol
Salvianolic acid Chemical Properties
- Melting point:
- 164-167°C
- Boiling point:
- 858.7±65.0 °C(Predicted)
- Density
- 1.580±0.06 g/cm3(Predicted)
- storage temp.
- 2-8°C
- solubility
- H2O: ≥19mg/mL
- pka
- 2.78±0.10(Predicted)
- form
- powder
- color
- yellow
- BRN
- 2660108
- InChIKey
- YMGFTDKNIWPMGF-UCPJVGPRSA-N
Safety Information
- Safety Statements
- 24/25
- WGK Germany
- 3
- HS Code
- 29189900
Salvianolic acid Usage And Synthesis
Description
Salvianolic acid A is an antioxidant and free radical scavenging compound extracted from S. miltiorrhiza that has been investigated for its cardioprotective and chemopreventative properties. It has been reported to reduce leukocyte-endothelial adherence, as well as inhibit inflammation and matrix metalloproteinases, suppress apoptosis, and reduce lipid peroxidation in damaged cardiac tissue.
Chemical Properties
Yellow Solid
Uses
ISalvianolic acid A (Sal A) and salvianolic acid B (Sal B) were isolated and purified from the crude extract of Salvia miltiorrhiza. Antioxidant activities of Sal A and Sal B were also evaluated and the ABTS results showed that Sal A and Sal B exhibited high total antioxidant activities, their EC50 values were 1.35 0.00 and 1.43 0.01 .mu.g/mL.
Definition
ChEBI: Salvianolic acid A is a stilbenoid.
General Description
Salvianolic acid A is a phenolic acid, isolated from Danshen, a traditional Chinese medicine, commonly used for the treatment of bone loss, chronic renal failure, hepatocirrhosis, hepatitis, coronary heart disease and cerebrovascular disease.
Biochem/physiol Actions
Salvianolic acid A is cell protective antioxidant originally isolated from Salvia. It has been found to attenuate PDGF-induced ROS formation in hepatic stellate cells and protected against isoproterenol-induced myocardial damage in rats.
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Salvianolic acid(96574-01-5)Related Product Information
- VINYL PROPIONATE
- Folic acid
- Glycine
- Citric acid
- Salvianolic acid B
- 4-(4-CHLORO-BENZYLOXY)-PHENYLAMINE
- Ethyl 2-(Chlorosulfonyl)acetate
- Triethoxyvinylsilane
- N-Vinyl-2-pyrrolidone
- Salvianolic acid E
- Salvianolicacid C
- Ascoric Acid
- Silicone rubber,methyl-vinyl
- Vinyl resin
- Vinyl ester resin
- (R)-3-(4-HYDROXYPHENYL)LACTIC ACID
- Danshensu
- Phenethyl cinnamate