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Bis(2-methoxyethyl)aminosulfur trifluoride

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Bis(2-methoxyethyl)aminosulfur trifluoride Basic information

Product Name:
Bis(2-methoxyethyl)aminosulfur trifluoride
Synonyms:
  • DEOXO-FLUOR(R)
  • BIS(2-METHOXYETHYL)AMINO-SULFUR TRIFLUORIDE
  • BIS(2-METHOXYETHYL)AMINOSULPHUR TRIFLUORIDE
  • BAST Deoxo-Fluor ,Bis(2-methoxyethyl)aminosulfur trifluoride
  • 2-methoxy-N-(2-methoxyethyl)-N-(trifluoro-λ4-sulfanyl)ethanamine
  • Bis(6-methoxyethyl)aminosulfur trifluoride
  • bis(2-methoxyethyl)(trifluoro-λ-sulfanyl)amine
  • Deoxo-Fluor (Air Prods. Chem.)
CAS:
202289-38-1
MF:
C6H14F3NO2S
MW:
221.24
EINECS:
478-190-3
Product Categories:
  • Fluorinating Reagents
  • Nucleophilic Fluorinating Reagents
  • Fluorinating Reagents & Building Blocks for Fluorinated Biochemical Compounds
  • Synthetic Organic Chemistry
Mol File:
202289-38-1.mol
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Bis(2-methoxyethyl)aminosulfur trifluoride Chemical Properties

Boiling point:
>80°C
Density 
1.2 g/mL at 25 °C(lit.)
refractive index 
1.4270 to 1.4310
Flash point:
205 °F
storage temp. 
2-8°C
form 
liquid
pka
-7.46±0.70(Predicted)
Specific Gravity
1.2
color 
clear yellow
Merck 
14,2897
InChIKey
APOYTRAZFJURPB-UHFFFAOYSA-N
CAS DataBase Reference
202289-38-1(CAS DataBase Reference)
EPA Substance Registry System
Sulfur, trifluoro[2-methoxy-N-(2-methoxyethyl)ethanaminato-.kappa.N]-, (T-4)- (202289-38-1)
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Safety Information

Hazard Codes 
T,C,F
Risk Statements 
14-23/25-29-35-67-65-63-48/20-25-11-40-37-19
Safety Statements 
23-26-36/37/39-43-45-8-62-46-25-16
RIDADR 
UN REST
WGK Germany 
3
10-21
Hazard Note 
Toxic/Corrosive
HazardClass 
KEEP COLD, CORROSIVE
PackingGroup 
HS Code 
29319090

MSDS

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Bis(2-methoxyethyl)aminosulfur trifluoride Usage And Synthesis

Chemical Properties

Dark yellow-orange liquid

Uses

Reactant for:

  • Fluorination reactions
  • Preparation of fluorinated catechols via Umpolung based nucleophilic deoxyfluorination
  • Preparation of imidazole derivatives as CXCR3 antagonists
  • Ring expansion reactions
  • Synthesis of acyl azides from carboxylic acids
  • Aldehydes or ketones from carboxylic acids and Grignard reagents via in situ generation of Weinreb amides

Uses

Versatile, thermally stable nucleophilic fluorinating reagent.

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