Detomidine hydrochloride Chemical Properties

Melting point:

160°C

storage temp. 

Sealed in dry,Room Temperature

solubility 

DMSO (Slightly), Methanol (Slightly)

form 

Solid

color 

White to Off-White

Major Application

pharmaceutical (small molecule)

InChI

InChI=1S/C12H14N2.ClH/c1-9-4-3-5-11(10(9)2)6-12-7-13-8-14-12;/h3-5,7-8H,6H2,1-2H3,(H,13,14);1H

InChI

1S/C12H14N2.ClH/c1-9-4-3-5-11(10(9)2)6-12-7-13-8-14-12;/h3-5,7-8H,6H2,1-2H3,(H,13,14);1H

InChIKey

OIWRDXKNDCJZSM-UHFFFAOYSA-N

SMILES

[Cl-].[nH]1cncc1Cc2c(c(ccc2)C)C.[H+]

SMILES

C1(C=CC=C(C)C=1C)CC1N=CNC=1.Cl

Safety Information

RIDADR 

UN 2811 6.1 / PGIII

WGK Germany 

WGK 3

RTECS 

NI5160000

HS Code 

2933.29.4300

Storage Class

11 - Combustible Solids

Detomidine hydrochloride Usage And Synthesis

Chemical Properties

Off-White Solid

Uses

Detomidine Hydrochloride is an α-Adrenoceptor agonist with sedative and analgesic activity. Sedative.

Uses

α-Adrenoceptor agonist with sedative and analgesic activity. Sedative.

Uses

Detomidine produce dose-dependent sedative and analgesic effects, mediatated by activation of α2 catecholamine receptors.

Biological Activity

detomidine hydrochloride produce dose-dependent sedative and analgesic effects, is a nonnarcotic, synthetic α2-adrenergic agonist

Veterinary Drugs and Treatments

At present, detomidine is only approved for use as a sedative analgesic in horses, but it has been used clinically in other species.

IC 50

α adrenergic receptor

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