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sinapultide

Basic information Safety Supplier Related

sinapultide Basic information

Product Name:
sinapultide
Synonyms:
  • sinapultide
  • ATI 01
  • KL4 (peptide)
  • RWJ 45652
  • L-Lysine, L-lysyl-L-leucyl-L-leucyl-L-leucyl-L-leucyl-L-lysyl-L-leucyl-L-leucyl-L-leucyl-L-leucyl-L-lysyl-L-leucyl-L-leucyl-L-leucyl-L-leucyl-L-lysyl-L-leucyl-L-leucyl-L-leucyl-L-leucyl-
  • sinapultide USP/EP/BP
  • RWJ 45652 CAS No:138531-07-4
CAS:
138531-07-4
MF:
C126H238N26O22
MW:
2469.4
Mol File:
138531-07-4.mol
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sinapultide Chemical Properties

Boiling point:
2047.1±65.0 °C(Predicted)
Density 
1.093
pka
3.31±0.10(Predicted)
form 
Solid
color 
White to off-white
Sequence
H-Lys-Leu-Leu-Leu-Leu-Lys-Leu-Leu-Leu-Leu-Lys-Leu-Leu-Leu-Leu-Lys-Leu-Leu-Leu-Leu-Lys-OH
InChIKey
QSIRXSYRKZHJHX-TWXHAJHVSA-N
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sinapultide Usage And Synthesis

Uses

Pulmonary surfactant.

Uses

Sinapultide is defined as a synthetic peptide replacement for SP-B, designed from the charge distribution of the last 22 amino acids of SP-B, and is clinically used for the prevention of respiratory distress syndrome (RDS) in at-risk premature infants.

in vivo

Sinapultide-loaded microbubbles (MBs) (0.1 mg; nasal delivery; collected at 3, 6, 12 and 24 hours after LPS) improves pulmonary edema in lung injury and increases lung W/D weight in LPS-induced ALI mice[2].

sinapultideSupplier

Wuxi Zhongkun Biochemical Technology Co., Ltd.
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Hangzhou Peptide Biochem Co.,Ltd
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Creative Peptides
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Nanjing Leon Biological Technology Co., Ltd.
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17705183659
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Nanjing Peptide Biotech Ltd.
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025-58361106-805 15951641583
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zhao.xu@njpeptide.com