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tirotundin

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tirotundin Basic information

Product Name:
tirotundin
Synonyms:
  • NSC 249959
  • Tagitinin D
  • tirotundin
  • 2-Methylpropanoic acid (3aS,4R,6S,9R,10S,11aR)-dodecahydro-9-hydroxy-6,10-dimethyl-3-methylene-2-oxo-6,9-epoxycyclodeca[b]furan-4-yl ester
  • Propanoic acid, 2-methyl-, (3aS,4R,6S,9R,10S,11aR)-dodecahydro-9-hydroxy-6,10-dimethyl-3-methylene-2-oxo-6,9-epoxycyclodeca[b]furan-4-yl ester
  • Tirotundine
CAS:
56377-67-4
MF:
C19H28O6
MW:
352.42
Mol File:
56377-67-4.mol
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tirotundin Usage And Synthesis

Uses

Tirotundin (Tagitinin D) is a potent anti-inflammatory agent. Tirotundin inhibits the activation of NF-Kβ[1].

References

[1] Rüngeler P, et al. Study of three sesquiterpene lactones from Tithonia diversifolia on their anti-inflammatory activity using the transcription factor NF-kappa B and enzymes of the arachidonic acid pathway as targets. Planta Med. 1998 Oct;64(7):588-93. DOI:10.1055/s-2006-957527

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